Nano-sized MRI contrast agents with dendrimer cores

H Kobayashi, MW Brechbiel - Advanced drug delivery reviews, 2005 - Elsevier
Gadolinium-based MRI contrast agents (CAs) can be effective at a∼ 100-fold lower
concentration of Gadolinium ions in comparison to the concentration of Iodine atoms …

Dendrimer-based macromolecular MRI contrast agents: characteristics and application

H Kobayashi, MW Brechbiel - Molecular imaging, 2003 - journals.sagepub.com
Numerous macromolecular MRI contrast agents prepared employing relatively simple
chemistry may be readily available that can provide sufficient enhancement for multiple …

Biomedical Nanomagnetics: A Spin Through Possibilities in Imaging, Diagnostics, and Therapy

KM Krishnan - IEEE transactions on magnetics, 2010 - ieeexplore.ieee.org
Biomedical nanomagnetics is a multidisciplinary area of research in science, engineering
and medicine with broad applications in imaging, diagnostics and therapy. Recent …

Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes

L Josephson, MF Kircher, U Mahmood… - Bioconjugate …, 2002 - ACS Publications
A number of quantitative three-dimensional tomographic near-infrared fluorescence imaging
techniques have recently been developed and combined with MR imaging to yield highly …

Uptake of dextran‐coated monocrystalline iron oxides in tumor cells and macrophages

A Moore, R Weissleder… - Journal of Magnetic …, 1997 - Wiley Online Library
Although several dextran‐coated iron oxide preparations are in preclinical and clinical use,
little is known about the mechanism of uptake into cells. As these particles have been shown …

Gadolinium-based hybrid nanoparticles as a positive MR contrast agent

H Hifumi, S Yamaoka, A Tanimoto… - Journal of the …, 2006 - ACS Publications
A new nanoparticulate inorganic− organic hybrid-type positive contrast agent (CA),
PGP/dextran-K01, was synthesized based on a GdPO4 inorganic core as a relaxation-time …

Polyethylene glycol-covered ultra-small Gd2O3 nanoparticles for positive contrast at 1.5 T magnetic resonance clinical scanning

MA Fortin, RM Petoral, F Söderlind, A Klasson… - …, 2007 - iopscience.iop.org
The size distribution and magnetic properties of ultra-small gadolinium oxide crystals (US-
Gd 2 O 3) were studied, and the impact of polyethylene glycol capping on the relaxivity …

Delivery of diagnostic agents for magnetic resonance imaging

Y Okuhata - Advanced drug delivery reviews, 1999 - Elsevier
A review of contrast agents used for magnetic resonance imaging was made with regard to
methods of drug delivery using published literature. Since the clinical approval of Gd-DTPA …

Superparamagnetic iron oxide–enhanced MR imaging of head and neck lymph nodes

MG Mack, JO Balzer, R Straub, K Eichler, TJ Vogl - Radiology, 2002 - pubs.rsna.org
PURPOSE: To compare findings on superparamagnetic iron oxide (SPIO)–enhanced
magnetic resonance (MR) images of the head and neck with those from resected lymph …

Subcutaneous and intravenous delivery of diagnostic agents to the lymphatic system: applications in lymphoscintigraphy and indirect lymphography

SM Moghimi, B Bonnemain - Advanced drug delivery reviews, 1999 - Elsevier
Lymph node status is important in the staging of many malignancies. Although tissue
characterization by histologic analysis of biopsy samples may improve staging, noninvasive …