Isoxazole is a five membered heterocyclic compound having various pharmacological
actions. The great interest associated with isoxazoles and their derivatives is based on their …

Background Cancer is one of the most dangerous and widespread diseases in the world
today and it has risen to the position of the leading cause of death around the globe in the …

Cancer now is one of the leading causes of mortality in the world. There has been a lot of
effort to discover new anticarcinogenic agents that allow treatment with fewer side effects. A …

The 1, 3-Dipolar cycloaddition reactions are the classic reaction in modern synthetic organic
chemistry. The concept of these reactions was introduced by Huisgen and his co-workers in …

Isoxazole derivatives are one of the heterocyclic structures that have various biological
activities. Objective: This study aimed to design and synthesize novel isoxazole derivatives …

A series of isoxazole derivatives (2a-i) were synthesized by conventional method using
various substituted chlorovinyl benzaldehydes as precursors. Structures of all the …

Nitrile oxides have an illustrious history, some even known back in the nineteenth century,
fruitful development of the generation and their utility in synthetic principle has been …

Synthesis of some novel isoxazole derivatives and their molecular docking with enzymes
from CYP450 family carried out using erlotinib, gemcitabine and ketoconazole as reference …

An efficient and accessible procedure for the synthesis of 1, 3, 4-oxadiazines was
developed. Reaction involves the cyclocondensation of phenylhydrazones catalyzed by a …

In this work a preliminary step was preparation of 1-(3-((1H-imidazol-2-yl) diazenyl) phenyl)
ethan-1-one (1) via coupling of diazonium salt of m-amino acetophenone with imidazole in …