[HTML][HTML] Metastatic uveal melanoma: The final frontier

ES Rantala, MM Hernberg, S Piperno-Neumann… - Progress in Retinal and …, 2022 - Elsevier
Abstract Treatment of primary intraocular uveal melanoma has developed considerably, its
driver genes are largely unraveled, and the ways to assess its risk for metastases are very …

Uveal melanoma pathobiology: Metastasis to the liver

P Bustamante, L Piquet, S Landreville… - Seminars in cancer …, 2021 - Elsevier
Uveal melanoma (UM) is a type of intraocular tumor with a propensity to disseminate to the
liver. Despite the identification of the early driver mutations during the development of the …

Percutaneous hepatic perfusion with melphalan in patients with unresectable ocular melanoma metastases confined to the liver: a prospective phase II study

TS Meijer, MC Burgmans, EM de Leede… - Annals of Surgical …, 2021 - Springer
Background Ocular melanoma is the most common primary intraocular malignancy and has
a very poor prognosis once liver metastases occur. The aim of this study was to …

Five decades of enucleations for uveal melanoma in one center: More tumors with high risk factors, no improvement in survival over time

CDM Roelofsen, APA Wierenga… - Ocular Oncology and …, 2021 - karger.com
Background: In order to improve medical care for uveal melanoma (UM) patients, we need to
monitor disease and survival to guide our research efforts. We analyzed the data of UM …

Clinical determinants of long-term survival in metastatic uveal melanoma

EAT Koch, A Petzold, A Wessely, E Dippel… - Cancer Immunology …, 2022 - Springer
This study aimed to identify prognostic factors in patients with metastatic uveal melanoma
(UM) that were associated with long-term survival in a real-world setting. A total of 94 …

Early detection of metastatic uveal melanoma by the analysis of tumor‐specific mutations in cell‐free plasma DNA

CHD Le Guin, N Bornfeld, NE Bechrakis… - Cancer …, 2021 - Wiley Online Library
Background Eye salvaging therapy of malignant melanomas of the uvea can preserve the
eye in most cases, but still about half of patients die from metastatic disease. Previous …

Determinants of overall survival in patients with metastatic uveal melanoma

P Demkowicz, R Pointdujour‐Lim, S Miguez, Y Lee… - Cancer, 2023 - Wiley Online Library
Background Despite improvements in the treatment of primary uveal melanoma (UM),
patients with metastatic disease continue to exhibit poor survival. Methods A retrospective …

[HTML][HTML] The application of artificial intelligence in the analysis of biomarkers for diagnosis and management of uveitis and Uveal Melanoma: A systematic review

A Bassi, SH Krance, A Pucchio, DR Pur… - Clinical …, 2022 - ncbi.nlm.nih.gov
Purpose This study aims to identify the available literature describing the utilization of
artificial intelligence (AI) as a clinical tool in uveal diseases. Methods A comprehensive …

Clinical features and survival outcomes of ocular melanoma in a multi-ethnic Asian cohort

LLY Tan, J Hong, WL Goh, EWY Chang, VS Yang… - Scientific reports, 2020 - nature.com
Ocular melanomas are uncommon cancers in Southeast Asia unlike in the West. We
conducted a retrospective review of patients (n= 44) with histologically-proven ocular …

Risk-stratified systemic surveillance in uveal melanoma

JM Davanzo, EM Binkley, JF Bena… - British Journal of …, 2019 - bjo.bmj.com
Background/Aim Molecular prognostication provides clinically applicable prognostic
information for patients with uveal melanoma. Most ocular oncologists recommend intensive …