Type 1 diabetes mellitus (T1D) is a chronic disease characterized by an autoimmune
destruction of insulin-producing β-pancreatic cells. Although many advances have been …

Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin-producing β cells
located in the endocrine pancreas in areas known as islets of Langerhans. The current …

Interpretation of clinical trials to alter the decline in β-cell function after diagnosis of type 1
diabetes depends on a robust understanding of the natural history of disease. Combining …

Background: The honeymoon period (ie, partial remission) of type 1 diabetes mellitus is
characterized by reduced insulin requirements while good glycemic control is maintained …

OBJECTIVE To investigate the effect of exogenous as well as endogenous glucagon-like
peptide 1 (GLP-1) on postprandial glucose excursions and to characterize the secretion of …

Context: The aim of this review was to explore the pathogenic and clinical spectrum of type 1
diabetes, which includes a form of adult onset autoimmune diabetes usually referred to as …

Despite extensive and ongoing investigations of the immune mechanisms of autoimmune
diabetes in humans and animal models, there is much less information about the natural …

Type 1 diabetes, a chronic autoimmune disease, causes destruction of insulin-producing β-
cells over a period of years. Although many markers of the autoimmune process have been …

Type 1 diabetes is an insulin-dependent, autoimmune disease where the pancreatic β cells
are destroyed resulting in hyperglycemia. This multifactorial disease involves multiple …

Methods We searched Embase, PubMed and Cochrane for randomized controlled trials (no
time restrictions) that investigated combined insulin and GLP-1 treatment. The main …