Diagnosis, genetic control and preventive management of canine hip dysplasia: a review

MMD Ginja, AM Silvestre, JM Gonzalo-Orden… - The Veterinary …, 2010 - Elsevier
Despite expensive screening and breeding programmes, hip dysplasia (HD) continues to be
one of the most common orthopaedic diseases in dogs. The vast majority of dogs afflicted …

Canine elbow dysplasia: aetiopathogenesis and current treatment recommendations

J Michelsen - The Veterinary Journal, 2013 - Elsevier
Elbow dysplasia is a common debilitating condition of large and giant breed dogs.
Environmental factors and a complex genetic heritability play a role in predisposing dogs to …

Canine genomics and genetics: running with the pack

HG Parker, EA Ostrander - PLoS genetics, 2005 - journals.plos.org
The domestication of the dog from its wolf ancestors is perhaps the most complex genetic
experiment in history, and certainly the most extensive. Beginning with the wolf, man has …

Long-term genetic selection reduced prevalence of hip and elbow dysplasia in 60 dog breeds

AM Oberbauer, GG Keller, TR Famula - PloS one, 2017 - journals.plos.org
Canine hip dysplasia (CHD) and elbow dysplasia (ED) impact the health and welfare of all
dogs. The first formally organized assessment scheme to improve canine health centered on …

Canine hip dysplasia: A natural animal model for human developmental dysplasia of the hip

C Pascual‐Garrido, F Guilak, MF Rai… - Journal of …, 2018 - Wiley Online Library
Developmental dysplasia of the hip (DDH) in humans is a common condition that is
associated with hip pain, functional limitations, and secondary osteoarthritis (OA). Surgical …

Prevalence of canine hip dysplasia in Switzerland between 1995 and 2016—a retrospective study in 5 common large breeds

S Ohlerth, B Geiser, M Flückiger… - Frontiers in veterinary …, 2019 - frontiersin.org
Canine hip dysplasia (CHD) is a genetic disease, modulated by epigenetic and
environmental factors. To decrease the prevalence of CHD, the hip joints of many pure …

A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS) and candidate gene approaches

N Bartolomé, S Segarra, M Artieda, O Francino… - PLoS …, 2015 - journals.plos.org
Canine hip dysplasia is one of the most prevalent developmental orthopedic diseases in
dogs worldwide. Unfortunately, the success of eradication programs against this disease …

Genetic variation and genetic trends in hip and elbow dysplasia in Swedish Rottweiler and Bernese Mountain Dog

S Malm, WF Fikse, B Danell… - Journal of animal …, 2008 - Wiley Online Library
The aim of this study was to estimate genetic parameters and genetic trends for hip (HD) and
elbow dysplasia (ED) in Swedish Rottweiler (RW) and Bernese Mountain Dog (BMD) …

Genetic dissection of canine hip dysplasia phenotypes and osteoarthritis reveals three novel loci

L Mikkola, S Holopainen, T Pessa-Morikawa… - BMC genomics, 2019 - Springer
Background Hip dysplasia and osteoarthritis continue to be prevalent problems in veterinary
and human medicine. Canine hip dysplasia is particularly problematic as it massively affects …

Fragmented coronoid process in the dog: a heritable disease

J Temwichitr, PAJ Leegwater, HAW Hazewinkel - The Veterinary Journal, 2010 - Elsevier
Fragmented coronoid process (FCP) is one of the main diseases associated with elbow
dysplasia. FCP is often diagnosed in medium-to-large breed dogs with front leg lameness …