Brain multimodality monitoring: an update
M Oddo, F Villa, G Citerio - Current opinion in critical care, 2012 - journals.lww.com
Brain multimodality monitoring: an update : Current Opinion in Critical Care Brain multimodality
monitoring: an update : Current Opinion in Critical Care Log in or Register Subscribe to …
monitoring: an update : Current Opinion in Critical Care Log in or Register Subscribe to …
The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: potential implications for the current approach to chemoradiation
J Portnow, B Badie, M Chen, A Liu, S Blanchard… - Clinical Cancer …, 2009 - AACR
Purpose: Intracerebral microdialysis (ICMD) is an accepted method for monitoring changes
in neurochemistry from acute brain injury. The goal of this pilot study was to determine the …
in neurochemistry from acute brain injury. The goal of this pilot study was to determine the …
Microdialysis monitoring in clinical traumatic brain injury and its role in neuroprotective drug development
Injuries to the central nervous system continue to be vast contributors to morbidity and
mortality; specifically, traumatic brain injury (TBI) is the most common cause of death during …
mortality; specifically, traumatic brain injury (TBI) is the most common cause of death during …
Brain extracellular fluid protein changes in acute stroke patients
L Dayon, N Turck, T García-Berrocoso… - Journal of proteome …, 2011 - ACS Publications
In vivo human brain extracellular fluids (ECF) of acute stroke patients were investigated to
assess the changes in protein levels associated with ischemic damages. Microdialysates …
assess the changes in protein levels associated with ischemic damages. Microdialysates …
Moderate and severe traumatic brain injury induce early overexpression of systemic and brain gelatinases
A Vilalta, J Sahuquillo, A Rosell, MA Poca… - Intensive care …, 2008 - Springer
Objective Recent experimental evidence suggests that matrix metalloproteinases (MMPs)
are implicated in the pathophysiology of traumatic brain injury (TBI) by increasing blood …
are implicated in the pathophysiology of traumatic brain injury (TBI) by increasing blood …
Relationship between systemic glucose and cerebral glucose is preserved in patients with severe traumatic brain injury, but glucose delivery to the brain may become …
S Magnoni, C Tedesco, M Carbonara… - Critical care …, 2012 - journals.lww.com
Objective: To clarify the dynamics of glucose delivery to the brain and the effects of changes
in blood glucose after severe traumatic brain injury. Design: Retrospective analysis of a …
in blood glucose after severe traumatic brain injury. Design: Retrospective analysis of a …
Lactate and the lactate-to-pyruvate molar ratio cannot be used as independent biomarkers for monitoring brain energetic metabolism: a microdialysis study in patients …
J Sahuquillo, MA Merino, A Sánchez-Guerrero… - PloS one, 2014 - journals.plos.org
Background For decades, lactate has been considered an excellent biomarker for oxygen
limitation and therefore of organ ischemia. The aim of the present study was to evaluate the …
limitation and therefore of organ ischemia. The aim of the present study was to evaluate the …
Normobaric hyperoxia in traumatic brain injury: does brain metabolic state influence the response to hyperoxic challenge?
A Vilalta, J Sahuquillo, MA Merino, MA Poca… - Journal of …, 2011 - liebertpub.com
This study sought to investigate whether normobaric hyperoxia (NH) improves brain
oxygenation and brain metabolism in the early phase of severe and moderate traumatic …
oxygenation and brain metabolism in the early phase of severe and moderate traumatic …
Lack of correlation among intracerebral cytokines, intracranial pressure, and brain tissue oxygenation in patients with traumatic brain injury and diffuse lesions
J Perez-Barcena, J Ibanez, M Brell, C Crespí… - Critical care …, 2011 - journals.lww.com
Objectives: To determine the evolution of cytokine patterns using microdialysis in patients
with traumatic brain injury with diffuse lesions and to study the relationship between …
with traumatic brain injury with diffuse lesions and to study the relationship between …
Microdialysis for assessing intratumoral drug disposition in brain cancers: a tool for rational drug development
J Blakeley, J Portnow - Expert opinion on drug metabolism & …, 2010 - Taylor & Francis
Importance of the field: Many promising targeted agents and combination therapies are
being investigated for brain cancer. However, the results from recent clinical trials have been …
being investigated for brain cancer. However, the results from recent clinical trials have been …