Vaccine adjuvants: smart components to boost the immune system

R Bastola, G Noh, T Keum, S Bashyal, JE Seo… - Archives of pharmacal …, 2017 - Springer
Vaccination is an effective approach to prevent the consequences of infectious diseases.
Vaccines strengthen immunity and make individuals resistant to infections with pathogens …

Vaccine potentiation by combination adjuvants

B Levast, S Awate, L Babiuk, G Mutwiri, V Gerdts… - Vaccines, 2014 - mdpi.com
Adjuvants are crucial components of vaccines. They significantly improve vaccine efficacy by
modulating, enhancing, or extending the immune response and at the same time reducing …

Adjuvants for foot-and-mouth disease virus vaccines: recent progress

Y Cao - Expert review of vaccines, 2014 - Taylor & Francis
Foot-and-mouth disease (FMD) is a highly contagious and rapidly spreading disease of
cloven-hoofed animals. In most countries, animals are immunized with inactivated whole …

VP1 of foot-and-mouth disease virus induces apoptosis via the Akt signaling pathway

JM Peng, SM Liang, CM Liang - Journal of Biological Chemistry, 2004 - ASBMB
Foot-and-mouth disease virus (FMDV) binds to cellular integrins through an RGD motif in its
capsid protein, VP1. It is unclear, however, what kind of cellular event (s) are triggered after …

Production of FMDV virus-like particles by a SUMO fusion protein approach in Escherichia coli

CD Lee, YP Yan, SM Liang, TF Wang - Journal of Biomedical Science, 2009 - Springer
Virus-like particles (VLPs) are formed by the self-assembly of envelope and/or capsid
proteins from many viruses. Some VLPs have been proven successful as vaccines, and …

Application of a recombinant capsid polyprotein (P1) expressed in a prokaryotic system to detect antibodies against foot-and-mouth disease virus serotype O

JK Biswal, P Bisht, JK Mohapatra, R Ranjan… - Journal of virological …, 2015 - Elsevier
Foot-and-mouth disease (FMD) is a highly contagious epidemic disease of transboundary
importance. In India, the disease is endemic in nature and is controlled primarily by …

Induction of immunity in swine by purified recombinant VP1 of foot-and-mouth disease virus

JH Wang, CM Liang, JM Peng, JJ Shieh, MH Jong… - Vaccine, 2003 - Elsevier
VP1, a capsid protein of foot-and-mouth disease virus (FMDV), contains neutralizing
epitopes of the virus. Due to its poor water solubility, recombinant Escherichia coli derived …

Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease

AL Barnard, A Arriens, S Cox, P Barnett, B Kristensen… - Vaccine, 2005 - Elsevier
Pigs were vaccinated with the emergency inactivated foot-and-mouth disease virus (FMDV)
vaccine—water-in-oil-in-water emulsion with Montanide ISA206—known to protect after 3–5 …

Enhancement of the immunity to foot-and-mouth disease virus by DNA priming and protein boosting immunization

JJ Shieh, CM Liang, CY Chen, F Lee, MH Jong, SS Lai… - Vaccine, 2001 - Elsevier
Subunit vaccination is effective in eliciting humoral responses to a variety of viral antigens,
however, it has not generated persistent protective immunity to foot-and-mouth disease virus …

Protective immune response of the capsid precursor polypeptide (P1) of foot and mouth disease virus type 'O'produced in Pichia pastoris

V Balamurugan, R Renji, SN Saha, GR Reddy… - Virus Research, 2003 - Elsevier
Foot and mouth disease virus (FMDV) is the aetiological agent of a highly contagious
vesicular disease of cloven-hooved animals. The gene coding for the capsid polyprotein …