Human dendritic cells: their heterogeneity and clinical application potential in cancer immunotherapy

TA Patente, MP Pinho, AA Oliveira… - Frontiers in …, 2019 - frontiersin.org
Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …

Role of immunity and vaginal microbiome in clearance and persistence of human papillomavirus infection

L Ntuli, A Mtshali, G Mzobe, LJP Liebenberg… - Frontiers in cellular …, 2022 - frontiersin.org
Cervical cancer disproportionately affects women of reproductive age, with 80% of cases
occurring in low-and middle-income countries. Persistent infection with high-risk human …

Recent advances on the crosstalk between neutrophils and B or T lymphocytes

S Costa, D Bevilacqua, MA Cassatella, P Scapini - Immunology, 2019 - Wiley Online Library
An increasing body of literature supports a role for neutrophils as players in the orchestration
of adaptive immunity. During acute and chronic inflammatory conditions, neutrophils rapidly …

Stress keratin 17 and estrogen support viral persistence and modulate the immune environment during cervicovaginal murine papillomavirus infection

W Wang, ME Spurgeon, A Pope… - Proceedings of the …, 2023 - National Acad Sciences
A murine papillomavirus, MmuPV1, infects both cutaneous and mucosal epithelia of
laboratory mice and can be used to model high-risk human papillomavirus (HPV) infection …

B lymphocytes can be activated to act as antigen presenting cells to promote anti-tumor responses

RAM Rossetti, NPC Lorenzi, K Yokochi, MBSF Rosa… - PloS one, 2018 - journals.plos.org
Immune evasion by tumors includes several different mechanisms, including the inefficiency
of antigen presenting cells (APCs) to trigger anti-tumor T cell responses. B lymphocytes may …

Vaginal microbiota and HPV infection: novel mechanistic insights and therapeutic strategies

Y Li, T Yu, H Yan, D Li, T Yu, T Yuan… - Infection and drug …, 2020 - Taylor & Francis
Cervical cancer is a global public health concern. The complex interaction of genetic and
environmental factors is critical for the progress of cervical cancer. Growing evidence …

Activities of stromal and immune cells in HPV-related cancers

MR Barros, CML de Melo, MLCMGR Barros… - Journal of Experimental …, 2018 - Springer
The immune system is composed of immune as well as non-immune cells. As this system is
a well-established component of human papillomavirus-(HPV)-related carcinogenesis, high …

[HTML][HTML] Identification of pyroptosis-related signature for cervical cancer predicting prognosis

C Zhou, C Li, Y Zheng, X Liu - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Cervical cancer (CC) is one of the most common malignancies encountered in gynecology
practice. However, there is a paucity of information about specific biomarkers that assist in …

Deciphering the roles of myeloid derived suppressor cells in viral oncogenesis

A Glover, Z Zhang, C Shannon-Lowe - Frontiers in immunology, 2023 - frontiersin.org
Myeloid derived suppressor cells (MDSCs) are a heterogenous population of myeloid cells
derived from monocyte and granulocyte precursors. They are pathologically expanded in …

Lactate secreted by cervical cancer cells modulates macrophage phenotype

SC Stone, RAM Rossetti, KLF Alvarez… - Journal of leukocyte …, 2019 - academic.oup.com
Cervical cancer continues to be a public health problem in developing countries. Previous
studies have shown that cervical cancer cells display markers of aerobic glycolysis …