Targeting Nuclear Mechanics Mitigates the Fibroblast Invasiveness in Pathological Dermal Scars Induced by Matrix Stiffening

X Fu, A Taghizadeh, M Taghizadeh, CJ Li… - Advanced …, 2024 - Wiley Online Library
Pathological dermal scars such as keloids present significant clinical challenges lacking
effective treatment options. Given the distinctive feature of highly stiffened scar tissues …

Spatially resolved single-molecule profiling of microRNAs in migrating cells driven by microconfinement

Z Fan, B Li, YJ Wang, X Huang, B Li, S Wang, Y Liu… - Chemical …, 2022 - pubs.rsc.org
Cancer cells utilize a range of migration modes to navigate through a confined tissue
microenvironment in vivo, while regulatory roles of key microRNAs (miRNAs) remain …

Femtosecond Laser Maskless Optical Projection Lithography of Cartilage PCM Inspired 3D Protein Matrix to Chondrocyte Phenotype

T Li, J Liu, M Guo, FC Bin, Q Duan… - Advanced …, 2024 - Wiley Online Library
Hydrogels containing chondrocytes have exhibited excellent potential in regenerating
hyaline cartilage. However, chondrocytes are vulnerable to dedifferentiation during in vitro …