Gram-negative bacteria characteristically are surrounded by an additional membrane layer,
the outer membrane. Although outer membrane components often play important roles in …

The interaction of antimicrobial peptides (AMPs) with biological membranes is in the focus of
research since several years, and the most important features and modes of action of AMPs …

In the present study, we have tried to establish the correlation between changes in Zeta
potential with that of cell surface permeability using bacteria (Escherichia coli and …

β-Defensins are small antimicrobial peptides of the innate immune system produced in
response to microbial infection of mucosal tissue and skin. We demonstrate that murine β …

The emergence of microbial resistance is becoming a global problem in clinical and
environmental areas. As such, the development of drugs with novel modes of action will be …

Ion channels on the mitochondrial inner membrane influence cell function in specific ways
that can be detrimental or beneficial to cell survival. At least one type of potassium (K+) …

Synthetic macromolecular antimicrobials have shown efficacy in the treatment of multidrug
resistant (MDR) pathogens. These synthetic macromolecules, inspired by Nature's …

Photodynamic inactivation of microorganisms (aPDI) is an excellent method to destroy
antibiotic-resistant microbial isolates. The use of an exogenous photosensitizer or irradiation …

Islet amyloid polypeptide (IAPP) is a 37-residue hormone that forms cytotoxic amyloid fibers
in the endocrine pancreas of patients with type II diabetes (NIDDM). A potential origin for …

Overcoming the global concern of antibiotic resistance is one of the biggest challenges
faced by scientists today, and the key to tackling this issue of emerging infectious diseases is …