Mathematical models of cystic fibrosis as a systemic disease
Cystic fibrosis (CF) is widely known as a disease of the lung, even though it is in truth a
systemic disease, whose symptoms typically manifest in gastrointestinal dysfunction first. CF …
systemic disease, whose symptoms typically manifest in gastrointestinal dysfunction first. CF …
Hepatic cholesterol biosynthesis and dioxin-induced dysregulation: A multiscale computational approach
Humans are constantly exposed to lipophilic persistent organic pollutants (POPs) that
accumulate in fatty foods. Among the numerous POPs, dioxins, in particular 2, 3, 7, 8 …
accumulate in fatty foods. Among the numerous POPs, dioxins, in particular 2, 3, 7, 8 …
Is the ENaC dysregulation in CF an effect of protein-lipid interaction in the membranes?
B Strandvik - International Journal of Molecular Sciences, 2021 - mdpi.com
While approximately 2000 mutations have been discovered in the gene coding for the cystic
fibrosis transmembrane conductance regulator (CFTR), only a small amount (about 10%) is …
fibrosis transmembrane conductance regulator (CFTR), only a small amount (about 10%) is …
Innate Immune Response of Airway Epithelial Cells from Children with Cystic Fibrosis to Rhinovirus Infection
KM Ling - 2021 - research-repository.uwa.edu.au
A common cold virus (rhinovirus) infection in young children with CF can cause more severe
impacts, such as hospitalisation, decline in lung function and excessive mucus production …
impacts, such as hospitalisation, decline in lung function and excessive mucus production …