Recent updates on animal models for understanding the etiopathogenesis of polycystic ovarian syndrome

L Corrie, M Gulati, SK Singh, B Kapoor, R Khursheed… - Life sciences, 2021 - Elsevier
Polycystic ovarian syndrome (PCOS) is the primary cause of female infertility affecting
several women worldwide. Changes in hormonal functions such as hyperandrogenism are …

[HTML][HTML] Pathophysiological mechanisms of gonadotropins–and steroid hormones–related genes in etiology of polycystic ovary syndrome

Z Shaaban, A Khoradmehr, MRJ Shirazi… - Iranian journal of basic …, 2019 - ncbi.nlm.nih.gov
Objective (s): Polycystic ovary syndrome (PCOS) is an endocrinopathy in women, which,
unlike its impact on fertility and health of women, there is no clear understanding about the …

Phytochemical-Based Study of Ethanolic Extract of Saraca asoca in Letrozole-Induced Polycystic Ovarian Syndrome in Female Adult Rats

N Bu, A Jamil, L Hussain, A Alshammari… - ACS …, 2023 - ACS Publications
Polycystic ovarian syndrome (PCOS) is a complex metabolic and endocrine disorder which
affects women of reproductive age. It is a condition in which ovaries produce an excessive …

Pathophysiology of obesity-related infertility and its prevention and treatment by potential phytotherapeutics

VVS Uddandrao, P Brahma Naidu… - International Journal of …, 2024 - nature.com
Background Obesity is a complex multifactorial disease in which the accumulation of excess
body fat has adverse health effects, as it can increase the risk of several problems, including …

[HTML][HTML] Protective effects of licorice extract on ovarian morphology, oocyte maturation, and embryo development in PCOS-induced mice: An experimental study

M Shamsi, V Nejati, G Najafi… - International journal of …, 2020 - ncbi.nlm.nih.gov
Background Polycystic ovary syndrome (PCOS) is an oxidative state resulting in ovarian
dysfunction. Licorice is one of the natural antioxidants used for the treatment of infertility …

High Fat Diet Exaggerate Metabolic and Reproductive PCOS Features by Promoting Oxidative Stress: An Improved EV Model in Rats

D Rakic, J Joksimovic Jovic, V Jakovljevic, V Zivkovic… - Medicina, 2023 - mdpi.com
Background and Objectives: Polycystic ovary syndrome (PCOS) is a frequent multifactorial
endocrinopathy affecting women in the reproductive period, often associated with infertility …

Assessment of Artemisia Campestris L. Leaf Extract Effects on Polycystic Ovarian Syndrome in Rats, Antioxidant and α‐Amylase Inhibition Activities

I Cherfi, N Mahboub, I Toumi… - Chemistry & …, 2024 - Wiley Online Library
Abstract Polycystic Ovarian Syndrome (PCOS) is characterized by metabolic and
reproductive dysfunction, often associated with elevated oxidative stress markers in the …

Apoptotic Cell Death via Activation of DNA Degradation, Caspase-3 Activity, and Suppression of Bcl-2 Activity: An Evidence-Based Citrullus colocynthis Cytotoxicity …

IA Shaikh, AM Alshabi, SA Alkahtani, MAA Orabi… - Separations, 2022 - mdpi.com
The objectives of this study are to investigate the cytotoxic effect of different Citrullus
colocynthis extracts on breast and lung cancer cell lines using flow cytometry to gain …

[HTML][HTML] Bioactive component of aqueous extract of Solanum melongena ameliorate estradiol valerate induced ovarian-pituitary dysfunctions in female Sprague …

SA Adelakun, OW Akintunde, GT Akingbade… - Phytomedicine Plus, 2022 - Elsevier
Background Estradiol valerate (EV) is known to cause hypothalamic-pituitary dysregulation
of the gonadotrophin-releasing hormone. This study focused on the impact of aqueous …

A review on pharmacological activities of Citrullus colocynthis (L.) Schrad

MSK Meybodi - Asian journal of Research and Reports …, 2020 - journal.article2publish.com
Plants are seen generally as resources for food and medicines by humans. Citrullus
colocynthis is a decorative European plant. It belongs to the Cucurbitaceae family and is …