Flavonoids as prospective neuroprotectants and their therapeutic propensity in aging associated neurological disorders

M Ayaz, A Sadiq, M Junaid, F Ullah, M Ovais… - Frontiers in aging …, 2019 - frontiersin.org
Modern research has revealed that dietary consumption of flavonoids and flavonoids-rich
foods significantly improve cognitive capabilities, inhibit or delay the senescence process …

Low-grade inflammation, diet composition and health: current research evidence and its translation

AM Minihane, S Vinoy, WR Russell, A Baka… - British Journal of …, 2015 - cambridge.org
The importance of chronic low-grade inflammation in the pathology of numerous age-related
chronic conditions is now clear. An unresolved inflammatory response is likely to be …

Management of oxidative stress and other pathologies in Alzheimer's disease

M Simunkova, SH Alwasel, IM Alhazza, K Jomova… - Archives of …, 2019 - Springer
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder, characterized by
the formation, aggregation and accumulation of amyloid beta, perturbed metal (copper, iron …

Understanding acquired brain injury: a review

L Goldman, EM Siddiqui, A Khan, S Jahan… - Biomedicines, 2022 - mdpi.com
Any type of brain injury that transpires post-birth is referred to as Acquired Brain Injury (ABI).
In general, ABI does not result from congenital disorders, degenerative diseases, or by brain …

Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG)

NA Singh, AKA Mandal, ZA Khan - Nutrition journal, 2015 - Springer
Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease
(PD) enforce an overwhelming social and economic burden on society. They are primarily …

Cocoa and chocolate in human health and disease

DL Katz, K Doughty, A Ali - Antioxidants & redox signaling, 2011 - liebertpub.com
Cocoa contains more phenolic antioxidants than most foods. Flavonoids, including catechin,
epicatechin, and procyanidins predominate in antioxidant activity. The tricyclic structure of …

Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects

D Vauzour - Oxidative medicine and cellular longevity, 2012 - Wiley Online Library
Accumulating evidence suggests that diet and lifestyle can play an important role in delaying
the onset or halting the progression of age‐related health disorders and to improve cognitive …

Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease

RJ Williams, JPE Spencer - Free Radical Biology and Medicine, 2012 - Elsevier
There is increasing evidence that the consumption of flavonoid-rich foods can beneficially
influence normal cognitive function. In addition, a growing number of flavonoids have been …

From cocoa to chocolate: Effect of processing on flavanols and methylxanthines and their mechanisms of action

L Goya, JE Kongor, S de Pascual-Teresa - International Journal of …, 2022 - mdpi.com
Despite the health benefits associated with the ingestion of the bioactive compounds in
cocoa, the high concentrations of polyphenols and methylxanthines in the raw cocoa beans …

The neuroprotective potential of flavonoids: a multiplicity of effects

D Vauzour, K Vafeiadou, A Rodriguez-Mateos… - Genes & nutrition, 2008 - Springer
Flavonoids exert a multiplicity of neuroprotective actions within the brain, including a
potential to protect neurons against injury induced by neurotoxins, an ability to suppress …