[HTML][HTML] Zebrafish models of human motor neuron diseases: advantages and limitations

PJ Babin, C Goizet, D Raldúa - Progress in neurobiology, 2014 - Elsevier
Motor neuron diseases (MNDs) are an etiologically heterogeneous group of disorders of
neurodegenerative origin, which result in degeneration of lower (LMNs) and/or upper motor …

Modeling neurodegenerative disorders in zebrafish

AA Bashirzade, KN Zabegalov, AD Volgin… - Neuroscience & …, 2022 - Elsevier
Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …

Visualization of cortical, subcortical and deep brain neural circuit dynamics during naturalistic mammalian behavior with head-mounted microscopes and chronically …

SL Resendez, JH Jennings, RL Ung… - Nature protocols, 2016 - nature.com
Genetically encoded calcium indicators for visualizing dynamic cellular activity have greatly
expanded our understanding of the brain. However, owing to the light-scattering properties …

Parp1 promotes sleep, which enhances DNA repair in neurons

D Zada, Y Sela, N Matosevich, A Monsonego… - Molecular cell, 2021 - cell.com
The characteristics of the sleep drivers and the mechanisms through which sleep relieves
the cellular homeostatic pressure are unclear. In flies, zebrafish, mice, and humans, DNA …

Zebrafish models of neurodevelopmental disorders: limitations and benefits of current tools and techniques

R Vaz, W Hofmeister, A Lindstrand - International journal of molecular …, 2019 - mdpi.com
For the past few years there has been an exponential increase in the use of animal models
to confirm the pathogenicity of candidate disease-causing genetic variants found in patients …

Benefits of zebrafish xenograft models in cancer research

X Chen, Y Li, T Yao, R Jia - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
As a promising in vivo tool for cancer research, zebrafish have been widely applied in
various tumor studies. The zebrafish xenograft model is a low-cost, high-throughput tool for …

Study on the toxic-mechanism of triclosan chronic exposure to zebrafish (Danio rerio) based on gut-brain axis

Y Wang, J Song, X Wang, Q Qian, H Wang - Science of the Total …, 2022 - Elsevier
Triclosan (TCS), as a broad-spectrum bactericide, is extensively used in the fine chemical
and textile industries. It is recognized as a new type of environmental endocrine disruptor …

Optical mapping of neuronal activity during seizures in zebrafish

L Turrini, C Fornetto, G Marchetto, MC Müllenbroich… - Scientific reports, 2017 - nature.com
Mapping neuronal activity during the onset and propagation of epileptic seizures can
provide a better understanding of the mechanisms underlying this pathology and improve …

The zebrafish for preclinical psilocybin research

OA Syed, B Tsang, R Gerlai - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
In this review, we discuss the possible utility of zebrafish in research on psilocybin, a
psychedelic drug whose recreational use as well as possible clinical application are gaining …

[HTML][HTML] Evaluation of cadmium and mercury on cardiovascular and neurological systems: Effects on humans and fish

A Naija, HC Yalcin - Toxicology Reports, 2023 - Elsevier
Chemicals are at the top of public health concerns and metals have received much attention
in terms of toxicological studies. Cadmium (Cd) and mercury (Hg) are among the most toxic …