[HTML][HTML] The 2022 World Health Organization classification of tumours of the urinary system and male genital organs—part A: renal, penile, and testicular tumours
The fifth edition of the World Health Organization (WHO) classification of urogenital tumours
(WHO “Blue Book”), published in 2022, contains significant revisions. This review …
(WHO “Blue Book”), published in 2022, contains significant revisions. This review …
Succinate dehydrogenase (SDH)‐deficient neoplasia
AJ Gill - Histopathology, 2018 - Wiley Online Library
The succinate dehydrogenase (SDH) complex is a key respiratory enzyme composed of four
subunits: SDHA, SDHB, SDHC and SDHD. Remarkably, immunohistochemistry for SDHB …
subunits: SDHA, SDHB, SDHC and SDHD. Remarkably, immunohistochemistry for SDHB …
[HTML][HTML] New developments in existing WHO entities and evolving molecular concepts: The Genitourinary Pathology Society (GUPS) update on renal neoplasia
K Trpkov, O Hes, SR Williamson, AJ Adeniran… - Modern Pathology, 2021 - Elsevier
Abstract The Genitourinary Pathology Society (GUPS) reviewed recent advances in renal
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …
New and emerging renal entities: a perspective post‐WHO 2016 classification
K Trpkov, O Hes - Histopathology, 2019 - Wiley Online Library
Renal tumours include a heterogeneous and diverse spectrum of neoplasms. Recent
advances in this field have significantly improved our understanding of the morphological …
advances in this field have significantly improved our understanding of the morphological …
Familial kidney cancer: implications of new syndromes and molecular insights
Context Hereditary cases account for about 5% of all cases of renal cell carcinoma (RCC).
With advances in next-generation sequencing, several new hereditary syndromes have …
With advances in next-generation sequencing, several new hereditary syndromes have …
Integrated molecular characterization of fumarate hydratase–deficient renal cell carcinoma
Purpose: Fumarate hydratase–deficient renal cell carcinoma (FH-deficient RCC) is a rare
but lethal subtype of RCC. Little is known about the genomic profile of FH-deficient RCC …
but lethal subtype of RCC. Little is known about the genomic profile of FH-deficient RCC …
Somatic mutations of TSC2 or MTOR characterize a morphologically distinct subset of sporadic renal cell carcinoma with eosinophilic and vacuolated cytoplasm
The differential diagnosis of renal cell neoplasms with solid or nested architecture and
eosinophilic cytoplasm has become increasingly complex. Despite recent advances in …
eosinophilic cytoplasm has become increasingly complex. Despite recent advances in …
A clinicopathologic and molecular analysis of fumarate hydratase-deficient renal cell carcinoma in 32 patients
HD Lau, E Chan, AC Fan, CA Kunder… - The American journal …, 2020 - journals.lww.com
Fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) is a rare and recently
described entity associated with hereditary leiomyomatosis and RCC syndrome. FH …
described entity associated with hereditary leiomyomatosis and RCC syndrome. FH …
[HTML][HTML] Germline and sporadic mTOR pathway mutations in low-grade oncocytic tumor of the kidney
Low-grade oncocytic tumor (LOT) of the kidney is a recently described entity with poorly
understood pathogenesis. Using next-generation sequencing (NGS) and complementary …
understood pathogenesis. Using next-generation sequencing (NGS) and complementary …
Re‐evaluation of 33 'unclassified'eosinophilic renal cell carcinomas in young patients
Aims We sought to determine if some unclassified renal cell carcinomas (RCC s) in children
and young adults that are characterised by predominantly eosinophilic cytoplasm are …
and young adults that are characterised by predominantly eosinophilic cytoplasm are …