Obesity is a multifactorial disease with both genetic and environmental components. The prevailing view is that obesity results from an imbalance between energy intake and …
Secondary bile acids (SBAs) are derived from primary bile acids (PBAs) in a process reliant on biosynthetic capabilities possessed by few microbes. To evaluate the role of BAs in …
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid disorders and metabolic syndrome have largely been attributed to genetic background and …
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
JJ Heindel, B Blumberg - Annual review of pharmacology and …, 2019 - annualreviews.org
Obesity is a worldwide pandemic in adults as well as children and adds greatly to health care costs through its association with type 2 diabetes, metabolic syndrome, cardiovascular …
DL Mendrick, AM Diehl, LS Topor… - Toxicological …, 2018 - academic.oup.com
Abstract Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic, a Society of Toxicology Contemporary Concepts in Toxicology (CCT) workshop was held on …
Non-alcoholic fatty liver disease (NAFLD) is often the hepatic expression of metabolic syndrome and its comorbidities that comprise, among others, obesity and insulin-resistance …
B Wang, EE Tsakiridis, S Zhang, A Llanos… - Nature …, 2021 - nature.com
Obesity results from a caloric imbalance between energy intake, absorption and expenditure. In both rodents and humans, diet-induced thermogenesis contributes to energy …
RJ Egusquiza, B Blumberg - Endocrinology, 2020 - academic.oup.com
The incidence of obesity has reached an all-time high, and this increase is observed worldwide. There is a growing need to understand all the factors that contribute to obesity to …