Cancer is a deadly disease with complicated pathology. Present chemotherapy regimen
encounters challenges such as cytotoxicity, non-specificity and development of drug …

The blood-brain barrier (BBB) restricts the access of therapeutic agents to the brain,
complicating the treatment of neurological diseases, such as Alzheimer's disease (AD) …

In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …

In the present report, three different shapes of chitosan-capped gold nanoparticles
(nanospheres, nanostars, and nanorods) were synthesized to investigate the effects of …

In recent years, several publications reported that nanoparticles larger than the kidney
filtration threshold were found intact in the urine after being injected into laboratory mice …

Advances in nanotechnology have had profound impacts on therapeutic delivery, leading to
the development of nanomaterials engineered with large carrying capabilities and targeting …

Achieving controlled cellular responses of nanoparticles (NP) is critical for the successful
development and translation of NP-based drug delivery systems. However, precise control …

This study investigated the role of nanoparticle size and surface chemistry on biocorona
composition and its effect on uptake, toxicity and cellular responses in human umbilical vein …

Nanoparticle (NP)-based drug delivery platforms have received a great deal of attention
over the past two decades for their potential in targeted cancer therapies. Despite the …

Technologies that induce antigen-specific immune tolerance by mimicking naturally
occurring mechanisms have the potential to revolutionize the treatment of many immune …