Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

A complex and multilayered immune defence system protects the host against harmful
agents and maintains tissue homeostasis. Cigarette smoke ex posure markedly impacts the …

Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

Cannabidiol (CBD), a natural phytocannabinoid without psychoactive effect, is a well-known
anti-inflammatory and antioxidant compound. The possibility of its use in cytoprotection of …

Reactive oxygen species (ROS) are involved in numerous physiological and
pathophysiological responses. Increasing evidence implicates ROS as signaling molecules …

Heme oxygenases (HOs) are the rate-limiting enzymes in the catabolism of heme into
biliverdin, free iron, and carbon monoxide. Two genetically distinct isoforms of HO have …

Microbial clearance by eukaryotes relies on complex and coordinated processes that remain
poorly understood. The gasotransmitter carbon monoxide (CO) is generated by the stress …

Butein and phloretin are chalcones that are members of the flavonoid family of polyphenols.
Flavonoids have well-known antioxidant and anti-inflammatory activities. In rat primary …

We examined the underlying mechanisms involved in n-3 docosahexaenoic acid (DHA)
inhibition of inflammation in EA. hy926 cells. The present results demonstrated that …

Unconjugated bilirubin (UCB) is responsible for neonatal jaundice and high level of free
bilirubin (Bf) can lead to kernicterus. Previous studies suggest that oxidative stress is a …