Cardiometabolic diseases (CMDs) are metabolic diseases (eg, obesity, diabetes,
atherosclerosis, rare genetic metabolic diseases, etc.) associated with cardiac pathologies …

Cardiac ageing manifests as a decline in function leading to heart failure. At the cellular
level, ageing entails decreased replicative capacity and dysregulation of cellular processes …

Background The aim of this study was to investigate the effects of low intensity exercise on
heart of streptozotocin (STZ)-induced diabetic rats. Materials and Methods The rats were …

Around the world there are 33.5 million patients suffering from atrial fibrillation (AF) with an
annual increase of 5 million cases. Most AF patients have an established form of an atrial …

Background Microvascular disease is associated with a high risk of macrovascular events in
patients with type 2 diabetes, but the impact of macrovascular disease on the risk of …

Diabetic cardiomyopathy (DCM) is a disorder of the heart muscle in people with diabetes
that can occur independent of hypertension or vascular disease. The underlying mechanism …

Aminolevulinic acid (5-ALA) is a naturally occurring amino acid and precursor of heme and
protoporphyrin IX (PpIX). Exogenously administrated 5-ALA increases the accumulation of …

Background: Physical exercise is a strategy to control hypertension and attenuate pressure
overload-induced cardiac remodeling. The influence of exercise on cardiac remodeling …

Aims/hypothesis Cyclophilin A, an immunophilin is secreted from human monocytes
activated by high glucose. Given its role as an inflammatory mediator of vascular tissue …

Background: Doxorubicin can cause cardiotoxicity. Matrix metalloproteinases (MMP) are
responsible for degrading extracellular matrix components which play a role in ventricular …