Acute kidney injury (AKI) is a common condition with a high risk of death. The standard
metrics used to define and monitor the progression of AKI, such as serum creatinine and …

Premature cardiovascular disease (CVD), including stroke, peripheral vascular disease,
sudden death, coronary artery disease, and congestive heart failure, is a notorious problem …

Because of its availability, ease of collection, and correlation with physiology and pathology,
urine is an attractive source for clinical proteomics/peptidomics. However, the lack of …

IgA nephropathy (IgAN) is the most common primary glomerulonephritis, frequently leading
to end-stage renal disease, as there is no disease-specific therapy. IgAN is diagnosed from …

Urine has become one of the most attractive biofluids in clinical proteomics as it can be
obtained non-invasively in large quantities and is stable compared with other biofluids. The …

Acute kidney injury (AKI) is associated with high morbidity and mortality. The lack of
sensitive and specific injury biomarkers has greatly impeded the development of therapeutic …

Acute kidney injury (AKI) is a common condition with significant associated morbidity and
mortality. Epidemiologic data suggest that a significant proportion of AKI cases is at least …

Diabetic nephropathy (DN) is a progressive kidney disease, a well-known complication of
long-standing diabetes. DN is the most frequent reason for dialysis in many Western …

A limitation of proteomic methods with respect to their clinical applicability is the lack of
possibilities to directly deduce the amount of a protein or peptide from a particular mass …

Urinary biomarkers for diabetes, diabetic nephropathy, and nondiabetic proteinuric renal
diseases were sought. For 305 individuals, biomarkers were defined and validated in …