Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders
G Novarino, AG Fenstermaker, MS Zaki, M Hofree… - science, 2014 - science.org
Hereditary spastic paraplegias (HSPs) are neurodegenerative motor neuron diseases
characterized by progressive age-dependent loss of corticospinal motor tract function …
characterized by progressive age-dependent loss of corticospinal motor tract function …
Regulation of intracellular signalling by the terminal membrane proteins of members of the Gammaherpesvirinae
MM Brinkmann, TF Schulz - Journal of general virology, 2006 - microbiologyresearch.org
The human γ 1-herpesvirus Epstein–Barr virus (EBV) and the γ 2-herpesviruses Kaposi's
sarcoma-associated herpesvirus (KSHV), rhesus rhadinovirus (RRV), herpesvirus saimiri …
sarcoma-associated herpesvirus (KSHV), rhesus rhadinovirus (RRV), herpesvirus saimiri …
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
The deubiquitinating enzyme USP1 controls the cellular levels of the DNA damage
response protein Ub-FANCD2, a key protein of the Fanconi anemia DNA repair pathway …
response protein Ub-FANCD2, a key protein of the Fanconi anemia DNA repair pathway …
T-cell transformation and oncogenesis by γ2-herpesviruses
A Ensser, B Fleckenstein - Advances in cancer research, 2005 - Elsevier
γ2-Herpesviruses, also termed rhadinoviruses, have long been known as animal pathogens
causing lymphoproliferative diseases such as malignant catarrhal fever in cattle or T-cell …
causing lymphoproliferative diseases such as malignant catarrhal fever in cattle or T-cell …
RAWUL: a new ubiquitin-like domain in PRC1 ring finger proteins that unveils putative plant and worm PRC1 orthologs
L Sanchez-Pulido, D Devos, ZR Sung, M Calonje - BMC genomics, 2008 - Springer
Abstract Background Polycomb group (PcG) proteins are a set of chromatin-modifying
proteins that play a key role in epigenetic gene regulation. The PcG proteins form large …
proteins that play a key role in epigenetic gene regulation. The PcG proteins form large …
Regulation of the Fanconi anemia pathway by a SUMO-like delivery network
K Yang, GL Moldovan, P Vinciguerra… - Genes & …, 2011 - genesdev.cshlp.org
The USP1/UAF1 complex deubiquitinates the Fanconi anemia protein FANCD2, thereby
promoting homologous recombination and DNA cross-link repair. How USP1/UAF1 is …
promoting homologous recombination and DNA cross-link repair. How USP1/UAF1 is …
Uncoordinated 119 protein controls trafficking of Lck via the Rab11 endosome and is critical for immunological synapse formation
MM Gorska, Q Liang, Z Karim, R Alam - The journal of immunology, 2009 - journals.aai.org
The activation of T cells through the TCR is essential for development of the adaptive
immune response. TCR does not have any enzymatic activity and relies on the plasma …
immune response. TCR does not have any enzymatic activity and relies on the plasma …
The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth
M Ohashi, AM Holthaus, MA Calderwood, CY Lai… - PLoS …, 2015 - journals.plos.org
The Epstein-Barr virus (EBV) nuclear proteins EBNA3A, EBNA3B, and EBNA3C interact with
the cell DNA binding protein RBPJ and regulate cell and viral genes. Repression of the …
the cell DNA binding protein RBPJ and regulate cell and viral genes. Repression of the …
Unraveling clonal CD8 T cell expansion and identification of essential factors in γ-herpesvirus-induced lymphomagenesis
M Gong, F Myster, A Azouz… - Proceedings of the …, 2024 - pnas.org
Alcelaphine gammaherpesvirus 1 (AlHV-1) asymptomatically persists in its natural host, the
wildebeest. However, cross-species transmission to cattle results in the induction of an acute …
wildebeest. However, cross-species transmission to cattle results in the induction of an acute …
Downregulation of the T-cell receptor complex and impairment of T-cell activation by human herpesvirus 6 u24 protein
BM Sullivan, L Coscoy - Journal of virology, 2008 - Am Soc Microbiol
We have performed a screen aimed at identifying human herpesvirus 6 (HHV-6)-encoded
proteins that modulate immune recognition. Here we show that the U24 protein encoded by …
proteins that modulate immune recognition. Here we show that the U24 protein encoded by …