Tumor cells evolve in a complex and heterogeneous environment composed of different cell
types and an extracellular matrix. Current 2D culture methods are very limited in their ability …

This April, the European Union (EU) prohibited selling new cosmetic products tested on
animals without any exemptions (1). Accordingly, it is forbidden to place a new product on …

Soft tissue reconstruction currently relies on two main approaches, one involving the
implantation of external biomaterials and the second one exploiting surgical autologous …

Autologous fat grafting offers significant promise for the repair of soft tissue deformities;
however, high resorption rates indicate that engineered solutions are required to improve …

Methods A literature review was conducted between April and June 2023 on PubMed and
Google Scholar Databases. All English and French articles related to bioengineering …

BACKGROUND: Breast cancer patients suffer from lowered quality of life (QoL) after surgery.
Breast conservancy surgery (BCS) such as partial mastectomy is being practiced and …

Abdominoperineal amputation (AAP) is a gold standard procedure treating advanced
abdominal and pelvic cancers. The defect resulting from this extensive surgery must be …

Background: Currently, the gold standard for complex defect reconstruction is autologous
tissue flaps, with vascularized composite allografts as its highest level. Good clinical results …

Autologous fat grafting is the gold standard for treatment in patients with soft-tissue defects.
However, the technique has a major limitation of unpredictable fat resorption due to …

Scaffold-guided breast tissue regeneration (SGBTR) can transform both reconstructive and
cosmetic breast surgery. Implant-based surgery is the most common method. However …