The purpose of this review is to summarize essential pharmacological, pharmaceutical, and
clinical aspects in the field of orally inhaled therapies that may help scientists seeking to …

The inhalation route is frequently used to administer drugs for the management of
respiratory diseases such as asthma or chronic obstructive pulmonary disease. Compared …

Lung cancer (LC) is one of the leading causes of mortality accounting for almost 25% of
cancer deaths throughout the world. The shortfall of affordable and effective first-line …

Liposomes and liposomes-based drug delivery systems are promising carriers in the rapidly
evolving field of nanomedicine. Liposomes are receiving growing attention in the scientific …

Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

New approaches are needed to assess the effects of inhaled substances on human health.
These approaches will be based on mechanisms of toxicity, an understanding of dosimetry …

With rapid advances in micro-fabrication processes and the availability of biologically-
relevant lung cells, the development of lung-on-chip platforms is offering novel avenues for …

Organic cation transporters (OCT) 1, 2 and 3 and novel organic cation transporters (OCTN) 1
and 2 of the solute carrier 22 (SLC22) family are involved in the cellular transport of …

Pulmonary delivery has gained increased interests over the past few decades. For
conditions within the respiratory tract, targeted drug delivery directly to the site of action can …

Despite the devastating impact of many lung diseases on human health, there is still a
significant unmet medical need in respiratory diseases, for which inhaled delivery …