Origin recognition complex (ORC), a heteromeric six-subunit complex, is the central
component of the eukaryotic pre-replication complex. Recent data from yeast, frogs, flies and …

Total number born (TNB), number of stillborn (NSB), and gestation length (GL) are
economically important traits in pig production, and disentangling the molecular …

The origin recognition complex (ORC) proteins, ORC1-6, are the first known proteins that
bind DNA replication origins to mark the competency for the initiation of DNA synthesis …

Graphical Abstract Abstract The transition of maternal to zygotic gene expression regulation
is critical for human preimplantation embryo development. In recent years, single-cell RNA …

In mammals, journey from metaphase‐I (M‐I) to metaphase‐II (M‐II) is important since
oocyte extrude first polar body (PB‐I) and gets converted into haploid gamete. The …

Origin recognition complex subunit 4 (ORC4) is a DNA-binding protein required for DNA
replication. During oocyte maturation, after the last oocyte DNA replication step and before …

Abstract The B6. YTIR (XY) mouse develops bilateral ovaries despite the expression of the
testis-determining gene Sry during gonadal differentiation. We reported that the oocytes of …

ABSTRACT The Origin Replication Complex subunit 4 (ORC4) is one in six subunits of the
Origin Replication Complexes (ORCs) which is essential for initiating licensing at DNA …

We have previously shown that the DNA replication licensing factor ORC4 forms a cage
around the chromosomes that are extruded in both polar bodies during murine oogenesis …

Parthenogenesis activation (PA), as an important artificial breeding method, can stably
preserve the dominant genotype of a species. However, the delayed development of PA …