[HTML][HTML] Anxiety, depression, and the microbiome: a role for gut peptides
The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …
[HTML][HTML] Ghrelin
Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …
Muscle wasting and cachexia in heart failure: mechanisms and therapies
S Von Haehling, N Ebner, MR Dos Santos… - Nature Reviews …, 2017 - nature.com
Body wasting is a serious complication that affects a large proportion of patients with heart
failure. Muscle wasting, also known as sarcopenia, is the loss of muscle mass and strength …
failure. Muscle wasting, also known as sarcopenia, is the loss of muscle mass and strength …
The endocrine manifestations of anorexia nervosa: mechanisms and management
M Schorr, KK Miller - Nature reviews endocrinology, 2017 - nature.com
Anorexia nervosa is a psychiatric disorder characterized by altered body image, persistent
food restriction and low body weight, and is associated with global endocrine dysregulation …
food restriction and low body weight, and is associated with global endocrine dysregulation …
[HTML][HTML] The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
The gastrointestinal peptide hormone ghrelin stimulates appetite in rodents and humans via
hypothalamic actions. We discovered expression of ghrelin in a previously uncharacterized …
hypothalamic actions. We discovered expression of ghrelin in a previously uncharacterized …
Ghrelin: structure and function
M Kojima, K Kangawa - Physiological reviews, 2005 - journals.physiology.org
Small synthetic molecules called growth hormone secretagogues (GHSs) stimulate the
release of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein …
release of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein …
Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-
releasing activity. This activity is mediated by the activation of the so-called GH …
releasing activity. This activity is mediated by the activation of the so-called GH …
Cancer cachexia—pathophysiology and management
H Suzuki, A Asakawa, H Amitani, N Nakamura… - Journal of …, 2013 - Springer
About half of all cancer patients show a syndrome of cachexia, characterized by anorexia
and loss of adipose tissue and skeletal muscle mass. Cachexia can have a profound impact …
and loss of adipose tissue and skeletal muscle mass. Cachexia can have a profound impact …
Endocrine consequences of anorexia nervosa
M Misra, A Klibanski - The lancet Diabetes & endocrinology, 2014 - thelancet.com
Anorexia nervosa is prevalent in adolescents and young adults, and endocrine changes
include hypothalamic amenorrhoea; a nutritionally acquired growth-hormone resistance …
include hypothalamic amenorrhoea; a nutritionally acquired growth-hormone resistance …
The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats
Y Date, N Murakami, K Toshinai, S Matsukura… - Gastroenterology, 2002 - Elsevier
Background & Aims: Visceral sensory information is transmitted to the brain through the
afferent vagus nerve. Ghrelin, a peptide primarily produced in the stomach, stimulates both …
afferent vagus nerve. Ghrelin, a peptide primarily produced in the stomach, stimulates both …