Uroprotective mechanisms of natural products against cyclophosphamide-induced urinary bladder toxicity: A comprehensive review

I Sherif - Acta Scientiarum Polonorum Technologia Alimentaria, 2020 - food.actapol.net
One of the widely used anticancer drugs for the treatment of various neoplasms is
cyclophosphamide (CYP). The inactive prodrug CYP is metabolized by cytochrome P450 …

Uroprotective mechanism of quercetin against cyclophosphamide‐induced urotoxicity: Effect on oxidative stress and inflammatory markers

IO Sherif - Journal of cellular biochemistry, 2018 - Wiley Online Library
The urotoxicity is a common complication associated with patients receiving
cyclophosphamide (CYP). This study was designed to investigate the uroprotective …

Uro-protective role of chrysin against cyclophosphamide-induced hemorrhagic cystitis in rats involving the turning-off NF-κB/P38-MAPK, NO/PARP-1 and STAT-3 …

DO Saleh, NMEA El-Nasr, AM Fayez, KA Ahmed… - Chemico-Biological …, 2023 - Elsevier
Background Chemotherapeutic agents are used to treat a wide range of cancer types, but
they cause serious side effects which must be managed after treatment. Cyclophosphamide …

[HTML][HTML] Can propolis and caffeic acid phenethyl ester be promising agents against cyclophosphamide toxicity?

S Akyol, MA Gulec, HK Erdemli… - Journal of Intercultural …, 2016 - ncbi.nlm.nih.gov
Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester
(CAPE). They have been using in several medical conditions/diseases in both in vitro and in …

Tropisetron ameliorates cyclophosphamide-induced hemorrhagic cystitis in rats

MR Zirak, G Karimi, R Rahimian, AH Jafarian… - European Journal of …, 2020 - Elsevier
Hemorrhagic cystitis is one of the most important complications of cyclophosphamide, a drug
widely used in cancer chemotherapy and bone marrow transplantation. 5-HT 3 antagonists …

A histopathological evaluation on the effect of captopril in cyclophosphamide-induced hemorrhagic cystitis

N Ahmadi, Z Rezaee, N Azarpira, S Zahedi… - Trends in …, 2021 - tips.sums.ac.ir
Cyclophosphamide is one of the most prescribed antineoplastic agents. Hemorrhagic cystitis
is one of the most common side effects of cyclophosphamide. Captopril is usually used as …

[HTML][HTML] Red propolis reduces inflammation in cyclophosphamide-induced hemorrhagic cystitis in rats

NO Ramos Melo, HDS Peres Júnior, CA Diniz… - Biomédica, 2022 - scielo.org.co
Introduction. Cyclophosphamide (CP) is used to treat malignant neoplasias and control
autoimmune diseases. Still, one of its metabolites, acrolein, is toxic to the urothelium and …

Untargeted Metabolomics Pilot Study Using UHPLC-qTOF MS Profile in Sows' Urine Reveals Metabolites of Bladder Inflammation

P Pousinis, C Virgiliou, T Mouskeftara, S Chalvatzi… - Metabolites, 2022 - mdpi.com
Urinary tract infections (UTI) of sows (characterized by ascending infections of the urinary
bladder (cyst), ureters, and renal pelvis), are major health issues with a significant economic …

Immuno-Biochemical Impacts of Gamma Irradiation in Male Rats: A Dose-Response Study

SM Hussien, ER Rashed - Dose-Response, 2023 - journals.sagepub.com
During radiotherapy, immune-modulatory effects of radiation doses should be taken into
consideration, not only the anti-tumor radiation effects. Thus, our study aimed to study how γ …

Evaluation of the Efficacy of Lactobacillus acidophilus in the Treatment of Cyclophosphamide-induced Hemorrhagic Cystitis in Wistar Rats

LF Minhos, AC da Silva de Lima Gehlen… - Current …, 2023 - benthamdirect.com
Background: Hemorrhagic cystitis is an inflammatory complication that can be caused by the
administration of cyclophosphamide, which is widely used as an antineoplastic agent. In the …