Leishmaniasis is a tropical disease caused by a protozoan parasite Leishmania that is
transmitted via infected female sandflies. At present, leishmaniasis treatment mainly counts …

The present paper aims to establish different treatments for neglected tropical disease by a
survey on drug conjugations and possible fixed-dose combinations (FDC) used to obtain …

The aim of this study was to develop, characterize and evaluate the in vivo oral efficacy of
self-emulsifying drug delivery systems (SEDDS) containing fexinidazole (FEX) in the …

Conformational restriction was addressed towards the development of more selective and
effective antileishmanial agents than currently used drugs for treatment of Leishmania …

Two new series of 28 selenocyanate and diselenide derivatives containing amide moieties
were designed, synthesized, and evaluated for their leishmanicidal activity against …

Leishmaniasis is caused by protozoan parasites of the genus Leishmania. An estimated 20
different Leishmania species, each with a particular drug response, are associated with …

Abstract Treatment against visceral leishmaniasis (VL) presents problems by the toxicity of
drugs, high cost and/or emergence of resistant strains. The diagnosis is hampered by …

Parasitic infections are prime causes of morbidity and mortality worldwide. Significant
progress has been made to cure these infections, such as discovering antiparasitic drugs …

Background: Neglected tropical diseases (NTDs) represent a serious problem in a number
of countries around the world and especially in Africa and South America, affecting mostly …

Leishmaniasis is an ongoing public health crisis and asks for unabated addressal by all
stakeholders. Efforts to eradicate the disease have been underway for over a decade. While …