Traumatic brain injury (TBI) presents in various forms ranging from mild alterations of
consciousness to an unrelenting comatose state and death. In the most severe form of TBI …

In its classic hormonal role, erythropoietin (EPO) is produced by the kidney and regulates
the number of erythrocytes within the circulation to provide adequate tissue oxygenation …

Erythropoietin (EPO), named after its role in hematopoiesis, is also expressed in mammalian
brain. In clinical settings, recombinant EPO treatment has revealed a remarkable …

Erythropoietin (EPO) is a glycoprotein cytokine known for its pleiotropic effects on various
types of cells and tissues. EPO and its receptor EPOR trigger signaling cascades …

Head trauma is the most common cause of disability in young adults. Known as a silent
epidemic, it can cause a mosaic of symptoms, whether neurological (sensory–motor …

Erythropoietin (EPO) is a glycoprotein that is mainly produced in the adult kidney, and it was
initially highlighted for its action on the hematopoietic system. Moreover, EPO is also …

Environmental enrichment of laboratory animals influences brain plasticity, stimulates
neurogenesis, increases neurotrophic factor expression, and protects against the effects of …

Perinatal brain injury frequently complicates preterm birth and leads to significant long‐term
morbidity. Cytokines and inflammatory cells are mediators in the common pathways …

Methods A systematic PubMed search up to June 2011 was undertaken to identify
medications with evidence of neuroprotection in pre-clinical studies when given either …

The growth factor erythropoietin (EPO) and erythropoietin receptors (EPOR) are expressed
in the nervous system. Neuronal expression of EPO and EPOR peaks during brain …