S100A8 and S100A9 in Cancer

Y Chen, Y Ouyang, Z Li, X Wang, J Ma - Biochimica et Biophysica Acta …, 2023 - Elsevier
Abstract S100A8 and S100A9 are Ca 2+ binding proteins that belong to the S100 family.
Primarily expressed in neutrophils and monocytes, S100A8 and S100A9 play critical roles in …

PPAR-α modulators as current and potential cancer treatments

Y Tan, M Wang, K Yang, T Chi, Z Liao, P Wei - Frontiers in oncology, 2021 - frontiersin.org
Cancer is one of the leading causes of mortality worldwide. PPAR modulators may hold
great potential for the management of cancer patients. Indeed, PPARs are critical sensors …

Strategy of targeting the tumor microenvironment via inhibition of fibroblast/fibrosis remodeling new era to cancer chemo-immunotherapy resistance

M Tajaldini, A Poorkhani, T Amiriani, A Amiriani… - European Journal of …, 2023 - Elsevier
The use of repurposing drugs that may have neoplastic and anticancer effects increases the
efficiency and decrease resistance to chemotherapy drugs through a biochemical and …

Advantages and drawbacks of dexamethasone in glioblastoma multiforme

AR Afshari, M Sanati, S Aminyavari, F Shakeri… - Critical Reviews in …, 2022 - Elsevier
The most widespread, malignant, and deadliest type of glial tumor is glioblastoma
multiforme (GBM). Despite radiation, chemotherapy, and radical surgery, the median …

PIWIL1 governs the crosstalk of cancer cell metabolism and immunosuppressive microenvironment in hepatocellular carcinoma

N Wang, HY Tan, Y Lu, YT Chan, D Wang… - … and Targeted Therapy, 2021 - nature.com
Altered energy metabolism of cancer cells shapes the immune cell response in the tumor
microenvironment that facilitates tumor progression. Herein, we reported the novel of tumor …

The role of the circadian clock in cancer hallmark acquisition and immune-based cancer therapeutics

E Cash, S Sephton, C Woolley, AM Elbehi, A RI… - Journal of Experimental …, 2021 - Springer
The circadian system temporally regulates physiology to maintain homeostasis. Co-opting
and disrupting circadian signals appear to be distinct attributes that are functionally …

Carnitine palmitoyltransferase system: a new target for anti-inflammatory and anticancer therapy?

M Wang, K Wang, X Liao, H Hu, L Chen… - Frontiers in …, 2021 - frontiersin.org
Lipid metabolism involves multiple biological processes. As one of the most important lipid
metabolic pathways, fatty acid oxidation (FAO) and its key rate-limiting enzyme, the carnitine …

Immunometabolism in the tumor microenvironment and its related research progress

Z Zhang, Y Hu, Y Chen, Z Chen, Y Zhu, M Chen… - Frontiers in …, 2022 - frontiersin.org
The tumor immune microenvironment has been a research hot spot in recent years. The
cytokines and metabolites in the microenvironment can promote the occurrence and …

IRF4 affects the protective effect of regulatory T cells on the pulmonary vasculature of a bronchopulmonary dysplasia mouse model by regulating FOXP3

Y Zhu, L He, Y Zhu, H Yao, J Jiang, H Lu - Molecular Medicine, 2024 - Springer
Background Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in
preterm infants, characterised by compromised alveolar development and pulmonary …

The involvement of trib3 and fabp1 and their potential functions in the dynamic process of gastric cancer

S Liu, C Ni, Y Li, H Yin, C Xing, Y Yuan… - Frontiers in Molecular …, 2021 - frontiersin.org
Background: Dysregulated expression of TRIB3 and FABP1 have been previously observed
in human cancer tissues. However, there are little information as to their expression change …