Conspectus The magnificent chemodiversity of more than 95 000 terpenoid natural products identified to date largely originates from catalysis by two types of terpene synthases …
All known triterpenes are generated by triterpene synthases (TrTSs) from squalene or oxidosqualene. This approach is fundamentally different from the biosynthesis of short-chain …
R Chen, Q Jia, X Mu, B Hu, X Sun… - Proceedings of the …, 2021 - National Acad Sciences
Chimeric terpene synthases, which consist of C-terminal prenyltransferase (PT) and N- terminal class I terpene synthase (TS) domains (termed PTTSs here), is unique to fungi and …
Covering: July 2012 to December 2019 Over the last seven years, expanding research efforts focused on sesterterpenoids has led to the isolation, identification, and …
Fusicoccadiene synthase from Phomopsis amygdali (PaFS) is a unique bifunctional terpenoid synthase that catalyzes the first two steps in the biosynthesis of the diterpene …
RA González-Hernández, NA Valdez-Cruz… - World Journal of …, 2023 - Springer
Terpenes and terpenoids are a group of isoprene-derived molecules that constitute the largest group of natural products and secondary metabolites produced by living things, with …
TA Pemberton, M Chen, GG Harris, WKW Chou… - Biochemistry, 2017 - ACS Publications
Terpenoid synthases catalyze isoprenoid cyclization reactions underlying the generation of more than 80,000 natural products. Such dramatic chemodiversity belies the fact that these …
T Mitsuhashi, I Abe - ChemBioChem, 2018 - Wiley Online Library
Prenyltransferase (PT) and terpene synthase (TPS) are key enzymes in the formation of the basic carbon skeletons of terpenoids. The PTs determine the prenyl carbon chain length …
NNQ Vo, Y Nomura, K Kinugasa, H Takagi… - ACS Chemical …, 2022 - ACS Publications
Natural drimane-type sesquiterpenes, including drimenol, display diverse biological activities. These active compounds are distributed in plants and fungi; however, their …