Biological Sex Is an Effect Modifier of Allergen-Mediated Alteration of the Lung Proteome

CL Marshall, D Mostafa, M Hemshehkar… - Journal of Proteome …, 2024 - ACS Publications
Asthma exhibits a distinct sex bias in the disease prevalence, severity, and response to
therapy. However, sex-related differences in alterations of the lung proteome mediated by …

Gonadal sex and chromosome complement influence the gut microbiome in a mouse model of allergic airway inflammation

CD Ekpruke, R Alford, E Parker… - Physiological …, 2024 - journals.physiology.org
Evidence abounds that gut microbiome components are associated with sex disparities in
the immune system. However, it remains unclear whether the observed sex disparity in …

Understanding the role of biological sex can optimize care and drug development in asthma

N Mookherjee, C Carlsten - Expert Review of Respiratory Medicine, 2024 - Taylor & Francis
Biological sex has a profound impact on health and disease, across different organ systems,
immunity, and response to therapy [1, 2]. The terms 'sex'and 'gender'are often conflated in …