Cellular magnesium homeostasis

AMP Romani - Archives of biochemistry and biophysics, 2011 - Elsevier
Magnesium, the second most abundant cellular cation after potassium, is essential to
regulate numerous cellular functions and enzymes, including ion channels, metabolic …

Traditional plant medicines as treatments for diabetes

CJ Bailey, C Day - Diabetes care, 1989 - Am Diabetes Assoc
More than 400 traditional plant treatments for diabetes mellitus have been recorded, but only
a small number of these have received scientific and medical evaluation to assess their …

The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life.

PJ Thornalley - Biochemical Journal, 1990 - ncbi.nlm.nih.gov
INTRODUCTION The glyoxalase system catalyses the conversion of methylglyoxal to D-
lactic acid via the intermediate SD-lactoylglutathione (Fig. 1). It comprises two enzymes …

A review of breath analysis for diagnosis of human health

KH Kim, SA Jahan, E Kabir - TrAC Trends in Analytical Chemistry, 2012 - Elsevier
In this review, we describe technical developments in breath analysis and its applications in
clinical diagnosis, monitoring disease state, and assessing environmental exposure. Breath …

Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification-a role in pathogenesis and antiproliferative …

PJ Thornalley - General Pharmacology: The Vascular System, 1996 - Elsevier
1. Methylglyoxal is a reactive α-oxoaldehyde and physiological metabolite formed by the
fragmentation of triose-phosphates, and by the metabolism of acetone and aminoacetone. 2 …

Breath analysis: potential for clinical diagnosis and exposure assessment

W Cao, Y Duan - Clinical chemistry, 2006 - academic.oup.com
Breath tests are among the least invasive methods available for clinical diagnosis, disease
state monitoring, and environmental exposure assessment. In recent years, interest in breath …

Smart hydrogels as functional biomimetic systems

HL Lim, Y Hwang, M Kar, S Varghese - Biomaterials Science, 2014 - pubs.rsc.org
Stimuli-responsive (smart) hydrogels have attracted widespread attention as biomimetic
systems due to their ability to respond to subtle changes in external and internal stimuli …

Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells

GE Mann, DL Yudilevich… - Physiological reviews, 2003 - journals.physiology.org
While transport processes for amino acids and glucose have long been known to be
expressed in the luminal and abluminal membranes of the endothelium comprising the …

Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic β-cells

K Sakai, K Matsumoto, T Nishikawa, M Suefuji… - Biochemical and …, 2003 - Elsevier
Pancreatic β-cells exposed to hyperglycemia produce reactive oxygen species (ROS).
Because β-cells are sensitive to oxidative stress, excessive ROS may cause dysfunction of β …

Soluble dietary fibre fraction of Trigonella foenum-graecum (fenugreek) seed improves glucose homeostasis in animal models of type 1 and type 2 diabetes by …

JMA Hannan, L Ali, B Rokeya, J Khaleque… - British Journal of …, 2007 - cambridge.org
Trigonella foenum-graecum (fenugreek) seeds have been documented as a traditional plant
treatment for diabetes. In the present study, the antidiabetic properties of a soluble dietary …