Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

MDA Paskeh, M Entezari, S Mirzaei, A Zabolian… - Journal of hematology & …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

Circular RNAs act as miRNA sponges

AC Panda - Circular RNAs: biogenesis and functions, 2018 - Springer
Majority of RNAs expressed in animal cells lack protein-coding ability. Unlike other cellular
RNAs, circular (circ) RNAs include a large family of noncoding (nc) RNAs that lack the 5′ or …

Circular RNAs open a new chapter in cardiovascular biology

S Aufiero, YJ Reckman, YM Pinto… - Nature Reviews …, 2019 - nature.com
Circular RNAs (circRNAs) are emerging as a new class of non-coding RNA molecules. This
unusual class of RNA species is generated by a back-splicing event of one or two exons …

Circular RNAs as emerging players in cervical cancer tumorigenesis; a review to roles and biomarker potentials

S Najafi - International Journal of Biological Macromolecules, 2022 - Elsevier
Cervical cancer is the most lethal gynecological cancer among women worldwide. Most of
the patients are diagnosed at the advanced stages due to late diagnosis and lack of …

Recent insights into the roles of circular RNAs in human brain development and neurologic diseases

S Najafi, SMA Zarch, J Majidpoor, S Pordel… - International Journal of …, 2023 - Elsevier
Circular RNAs (circRNAs) are a novel class of non-coding RNAs. They are single-stranded
RNA transcripts characterized with a closed loop structure making them resistant to …

The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p

S Wei, Y Zheng, Y Jiang, X Li, J Geng, Y Shen, Q Li… - …, 2019 - thelancet.com
Background Non-small cell lung carcinomas (NSCLC) are prevalent, lethal cancers with
especially grim prospects due to late-stage detection and chemoresistance. Circular RNAs …

DNMT1: A key drug target in triple-negative breast cancer

KK Wong - Seminars in cancer biology, 2021 - Elsevier
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer.
Altered epigenetics regulation including DNA hypermethylation by DNA methyltransferase 1 …

Circular RNA in exosomes

D Fanale, S Taverna, A Russo, V Bazan - Circular RNAs: biogenesis and …, 2018 - Springer
Circular RNAs (circRNAs) are a novel family of non-coding endogenous RNAs discovered in
all eukaryotic cells and generated through a particular mechanism of alternative splicing …

Circular RNA in renal diseases

J Jin, H Sun, C Shi, H Yang, Y Wu, W Li… - Journal of cellular …, 2020 - Wiley Online Library
Circular RNA (circRNA) is a newly described type of non‐coding RNA. Active research is
greatly enriching the current understanding of the expression and role of circRNA, and a …

Microarray is an efficient tool for circRNA profiling

S Li, S Teng, J Xu, G Su, Y Zhang, J Zhao… - Briefings in …, 2019 - academic.oup.com
Circular RNAs (circRNAs) are emerging as a new class of endogenous and regulatory
noncoding RNAs in latest years. With the widespread application of RNA sequencing (RNA …