Lung cancer (LC) has the highest relative risk of development as a comorbidity of chronic
obstructive pulmonary disease (COPD). The molecular mechanisms that mediate chronic …

The MYC transcription factor is one of the best characterized PP2A substrates. Deregulation
of the MYC oncogene, along with inactivation of PP2A, are two frequent events in cancer …

After spinal cord injury (SCI) in mammals, neuronal regeneration is limited; in contrast, such
regeneration occurs quickly in zebrafish. Member A of the acidic nuclear phosphoprotein 32 …

Glaucoma is a complex, multifactorial optic neuropathy mainly characterized by the
progressive loss of retinal ganglion cells (RGCs) and their axons, resulting in a decline of …

Background Acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) is a novel regulator
of histone H3 acetylation and promotes leukemogenesis in acute myeloid leukemia (AML) …

Acidic leucine rich nuclear phosphoprotein-32A (ANP32A) protein has a variety of functions,
such as regulating cell differentiation, influencing cell apoptosis and cell cycle progression …

Clinic therapy of acute myeloid leukemia (AML) remains unsatisfactory that urges for
development of novel strategies. Recent studies identified ANP32A as a novel biomarker of …

Acute megakaryoblastic leukaemia (AMKL) is characterized by expansion of
megakaryoblasts, which are hyper-proliferative cells that fail to undergo differentiation …

Mesothelioma is an aggressive tumor that affects thousands of people every year. The
therapeutic options for patients are limited; hence, a better understanding of mesothelioma …

Acute myeloid leukemia (AML) is a type of blood malignancies with high genetic
heterogeneity. Epigenetic alterations including histone acetylation have been found to be …