Over the past decade, organs-on-a-chip and microphysiological systems have emerged as a
disruptive in vitro technology for biopharmaceutical applications. By enabling new …

Healthy functioning of the female reproductive tract (FRT) depends on balanced and
dynamic regulation by hormones during the menstrual cycle, pregnancy and childbirth. The …

Cilia control homeostasis of the mammalian body by generating fluid flow. It has long been
assumed that ciliary length-control mechanisms are essential for proper flow generation …

Motile cilia are dynamic hair-like structures covering epithelial surfaces in multiple organs.
The periodic coordinated beating of cilia creates waves propagating along the surface …

The oviduct is an important organ in reproduction where fertilization occurs, and through
which the fertilized eggs are carried to the uterus in mammals. This organ is highly …

Hysterosalpingographies (HSGs) have formed an essential part of the fertility workup for
more than a century. More recently, tubal flushing, especially with oil-based contrast, has …

Organs and tissues in multi-cellular organisms exhibit various morphologies. Tubular organs
have multi-scale morphological features which are closely related to their functions. Here we …

The oviduct, or Fallopian tube in humans, transports oocytes and sperm, serves as the site of
fertilization, and supports early embryonic development. The oviduct is essential for fertility …

Motile cilia in the mammalian oviduct play a key role in reproduction, such as transporting
fertilized oocytes to the uterus for implantation. Due to their small size (~ 5–10 μm in length …

The molecular mechanisms by which cilia orientation is coordinated within and between
multi-ciliated cells (MCCs) are not fully understood. In the mouse oviduct, MCCs exhibit a …