The precision in the design and manufacturing of scaffolds with ideal properties such as
biocompatibility, biodegradability, mechanical and surface characteristics is very crucial for …

Polycaprolactone (PCL) is a bioresorbable and biocompatible polymer that has been widely
used in long-term implants and controlled drug release applications. However, when it …

Abstract 3D printing-based technologies can fabricate scaffolds offer great precision to
control internal architecture and print complicated structures based upon the defect site …

In recent years, significant development has been achieved in the construction of artificial
bone with ceramics, polymers and metals. Nano-hydroxyapatite (nHA) is widely used …

Tissue engineering is essentially a technique for imitating nature. Natural tissues consist of
three components: cells, signalling systems (eg growth factors) and extracellular matrix …

Bone tissue engineering is the technology of healing bone defects in critical clinical
conditions using functional tissue-engineering substitutes. Hydroxyapatite (HAp), as a …

A fine-tuned combination of scaffolds, biomolecules, and mesenchymal stem cells (MSCs) is
used in tissue engineering to restore the function of injured bone tissue and overcome the …

In recent years remarkable efforts have been made to produce artificial bone through tissue
engineering techniques. Silk fibroin (SF) and hydroxyapatite (HA) have been used in bone …

Repair of periodontal and maxillofacial bone defects is a major challenge in clinical. Guided
bone regeneration (GBR) is considered one of the most effective methods. However, the …

In this study, polycaprolactone (PCL) and polycaprolactone/fluoride substituted-
hydroxyapatite (PCL/FHA) nanocomposite coatings at different composition (10, 20 and 30 …