Interferon regulatory factors (IRFs) are a family of homologous proteins that regulate the
transcription of interferons (IFNs) and IFN-induced gene expression. As such they are …

Interferon regulatory factors (IRFs) play critical roles in pathogen-induced innate immune
responses and the subsequent induction of adaptive immune response. Dysregulation of …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by persistent synovial
inflammation. The major drivers of synovial inflammation are cytokines and chemokines …

Rheumatoid arthritis is characterized by progressive joint inflammation and affects~ 1% of
the human population. We noted single-nucleotide polymorphisms (SNPs) in the apoptotic …

HPV16 E6 oncoprotein is a member of the human papillomavirus (HPV) family that
contributes to enhanced cellular proliferation and risk of cervical cancer progression via viral …

Interferon Regulatory Factor (IRF)-1, originally identified as a transcription factor of the
human interferon (IFN)-β gene, mediates tumor suppression and may inhibit oncogenesis …

Current protocols for chondrocyte expansion and chondrogenic differentiation of stem cells
fail to reduce phenotypic loss and to mitigate hypertrophic tendency. To this end, cell genetic …

Aminopeptidase N/CD13 is expressed by fibroblast-like synoviocytes (FLS) and monocytes
(MNs) in inflamed human synovial tissue (ST). This study examined the role of soluble CD13 …

Background: The pathological activation of innate immune system may contribute to the
development of cardiometabolic diseases. The interferon regulatory factor (IRF) family …

Objective To determine the role of α (1, 2)‐linked fucosylation of proteins by
fucosyltransferase 1 (FUT1) in rheumatoid arthritis (RA) angiogenesis. Methods Analysis of …