Sulfatases, which cleave sulfate esters in biological systems, play a key role in regulating
the sulfation states that determine the function of many physiological molecules. Sulfatase …

The sulfonation (also known as sulfurylation) of biomolecules has long been known to take
place in a variety of organisms, from prokaryotes to multicellular species, and new biological …

Completely revised and expanded to reflect the latest advancements in the field,
Polysaccharides: Structural Diversity and Functional Versatility, Second Edition outlines …

Heparan sulfate (HS) proteoglycans at cell surfaces and in the extracellular matrix of most
animal tissues are essential in development and homeostasis, and variously implicated in …

Over the past decade, the glycosaminoglycans heparin and heparan sulfate have been
shown to bind and regulate the activities of many proteins. Established techniques have …

Heparan sulfate (HS) proteoglycans are crucial to numerous biological processes and
pathological conditions, but to date only a few HS structures have been synthesized and …

Fibroblast growth factor (FGF) signaling begins with the formation of a ternary complex of
FGF, FGF receptor (FGFR), and heparan sulfate (HS). Multiple models have been proposed …

▪ Abstract Heparan sulfate (HS) binds numerous extracellular ligands, including cell-cell
signaling molecules and their signal-transducing receptors. Ligand binding sites in HS have …

Heparan sulfate, a cell surface bound glycosaminoglycan polysaccharide, has been
implicated in numerous biological functions. Heparan sulfate molecules are highly complex …

Synthetic scaffolds show great promise for use in tissue engineering due to their ability to
mimic some aspects of the extracellular matrix, however, their use has been hindered by the …