Bilosomes as promising nanovesicular carriers for improved transdermal delivery: construction, in vitro optimization, ex vivo permeation and in vivo evaluation
Purpose The goal of this research was to enhance the transdermal delivery of lornoxicam
(LX), using nanovesicular carriers composed of the bile salt sodium deoxycholate (SDC) …
(LX), using nanovesicular carriers composed of the bile salt sodium deoxycholate (SDC) …
Corneal targeted Sertaconazole nitrate loaded cubosomes: preparation, statistical optimization, in vitro characterization, ex vivo permeation and in vivo studies
NF Younes, SA Abdel-Halim, AI Elassasy - International journal of …, 2018 - Elsevier
Sertaconazole nitrate (STZ) is a poorly soluble antifungal drug commonly used for treating
fungal skin infections. Introducing it as a new treatment option for the management of fungal …
fungal skin infections. Introducing it as a new treatment option for the management of fungal …
Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, in vitro characterization, ex vivo and in vivo …
The purpose of this manuscript was to develop and optimize Fenticonazole Nitrate (FTN)-
loaded novasomes aiming to enhance drug corneal penetration and to improve its …
loaded novasomes aiming to enhance drug corneal penetration and to improve its …
Sustained ocular delivery of Dorzolamide-HCl via proniosomal gel formulation: in-vitro characterization, statistical optimization, and in-vivo pharmacodynamic …
Glaucoma is the second cause of blindness worldwide. Frequent administration of traditional
topical dosage forms may lead to patient incompliance and failure of treatment. Our study …
topical dosage forms may lead to patient incompliance and failure of treatment. Our study …
Microemulsions as lipid nanosystems loaded into thermoresponsive in situ microgels for local ocular delivery of prednisolone
This study aimed to develop and evaluate thermoresponsive in situ microgels for the local
ocular delivery of prednisolone (PRD)(PRD microgels) to improve drug bioavailability and …
ocular delivery of prednisolone (PRD)(PRD microgels) to improve drug bioavailability and …
A comprehensive review on recent nanosystems for enhancing antifungal activity of fenticonazole nitrate from different routes of administration
This review aims to comprehensively highlight the recent nanosystems enclosing
Fenticonazole nitrate (FTN) and to compare between them regarding preparation …
Fenticonazole nitrate (FTN) and to compare between them regarding preparation …
Self-assembling lecithin-based mixed polymeric micelles for nose to brain delivery of clozapine: In-vivo assessment of drug efficacy via radiobiological evaluation
FM Elsharkawy, MM Amin… - International Journal …, 2023 - Taylor & Francis
Purpose The research objective is to design intranasal brain targeted CLZ loaded lecithin
based polymeric micelles (CLZ-LbPM) aiming to improve central systemic CLZ …
based polymeric micelles (CLZ-LbPM) aiming to improve central systemic CLZ …
PEGylated Lipid Polymeric Nanoparticle–Encapsulated Acyclovir for In Vitro Controlled Release and Ex Vivo Gut Sac Permeation
S Mahmood, KC Kiong, CS Tham, TC Chien… - Aaps Pharmscitech, 2020 - Springer
Currently, pharmaceutical research is directed wide range for developing new drugs for oral
administration to target disease. Acyclovir formulation is having common issues of short half …
administration to target disease. Acyclovir formulation is having common issues of short half …
Solutol HS15 based binary mixed micelles with penetration enhancers for augmented corneal delivery of sertaconazole nitrate: optimization, in vitro, ex vivo and in …
NF Younes, SA Abdel-Halim, AI Elassasy - Drug delivery, 2018 - Taylor & Francis
Keratomycosis is a serious corneal disease that can cause a permanent visual disability if
not treated effectively. Sertaconazole nitrate (STZ), a novel broad spectrum antifungal drug …
not treated effectively. Sertaconazole nitrate (STZ), a novel broad spectrum antifungal drug …
Enhanced transdermal delivery of ondansetron using nanovesicular systems: fabrication, characterization, optimization and ex-vivo permeation study-Box-Cox …
This study aimed to formulate suitable nanovesicles (NVs) for transdermal delivery of
Ondansetron. It also illustrated a practical example for the importance of Box-Cox …
Ondansetron. It also illustrated a practical example for the importance of Box-Cox …