Recent studies have brought forward the critical role of emergent properties in shaping
microbial communities and the ecosystems of which they are a part. Emergent properties …

The Lotka-Volterra (LV) model was introduced in the early 20th Century to describe predator-
prey systems. Since then, the model has been expanded to capture the dynamics of …

To alter microbial community composition for therapeutic purposes, an accurate and reliable
modeling framework capable of predicting microbial community outcomes is required. Lotka …

Cystic fibrosis (CF) is widely known as a disease of the lung, even though it is in truth a
systemic disease, whose symptoms typically manifest in gastrointestinal dysfunction first. CF …

This paper describes and validates an algorithm to solve optimal control problems for agent-
based models (ABMs). For a given ABM and a given optimal control problem, the algorithm …

The vision of personalized medicine is to identify interventions that maintain or restore a
person's health based on their individual biology. Medical digital twins, computational …

In an experimental setting, the composition of ecological communities can be manipulated
directly. Starting from a pool of n species, it is possible to co‐culture species in different …

Networks are ubiquitous throughout biology, spanning the entire range from molecules to
food webs and global environmental systems. Yet, despite substantial efforts by the scientific …

Abstract Lotka-Volterra (LV) and Multivariate Autoregressive (MAR) models are
computational frameworks with different mathematical structures that have both been …

Ecological communities, and microbial communities in particular, can consist of hundreds to
thousands of species interacting in a complex network. This complexity is the source of very …