The process of translation requires substantial cellular resources. Cells have therefore
evolved complex mechanisms to control overall protein synthesis as well as the translation …

Eukaryotic elongation factor 2 kinase (eEF2K) is a member of the small group of atypical 'α-
kinases'. It phosphorylates and inhibits eukaryotic elongation factor 2, to slow down the …

We tested the hypothesis that increasing blood amino acid (AA) availability would counter
the physical inactivity‐induced reduction in muscle protein synthesis. We determined how …

Cell proliferation exerts a high demand on protein synthesis, yet the mechanisms coupling
the two processes are not fully understood. A kinase and phosphatase screen for activators …

Translation is critical for development as transcription in the oocyte and early embryo is
silenced. To illustrate the translational changes during meiosis and consecutive two mitoses …

It is well established that the target of rapamycin (TOR) protein kinase has pivotal roles in
controlling cell functions (including protein synthesis, cell growth and cell proliferation) and …

Tumor cells are continually subjected to diverse stress conditions of the tumor
microenvironment, including hypoxia, nutrient deprivation, and oxidative or genotoxic stress …

Control of translation allows for the production of stoichiometric levels of each protein in the
cell. Attaining such a level of fine-tuned regulation of protein production requires the …

Based on own translational research of the biochemical and hormonal effects of cow's milk
consumption in humans, this review presents milk as a signaling system of mammalian …

Genes implicated in translation control have been associated with autism spectrum
disorders (ASDs). However, some important genetic causes of autism, including the 16p11 …