Friends with benefits: chemokines, glioblastoma-associated microglia/macrophages, and tumor microenvironment

E Codrici, ID Popescu, C Tanase, AM Enciu - International journal of …, 2022 - mdpi.com
Glioma is the most common primary intracranial tumor and has the greatest prevalence of all
brain tumors. Treatment resistance and tumor recurrence in GBM are mostly explained by …

CRISPR/Cas9-mediated gene therapy for glioblastoma: a scoping review

E Begagić, H Bečulić, N Đuzić, A Džidić-Krivić… - Biomedicines, 2024 - mdpi.com
This scoping review examines the use of CRISPR/Cas9 gene editing in glioblastoma (GBM),
a predominant and aggressive brain tumor. Categorizing gene targets into distinct groups …

Cluster miRNAs and cancer: Diagnostic, prognostic and therapeutic opportunities

SP Kabekkodu, V Shukla, VK Varghese… - Wiley …, 2020 - Wiley Online Library
MiRNAs are class of noncoding RNA important for gene expression regulation in many
plants, animals and viruses. MiRNA clusters contain a set of two or more miRNA encoding …

[HTML][HTML] MiR-125a-5p suppresses bladder cancer progression through targeting FUT4

Y Zhang, D Zhang, J Lv, S Wang, Q Zhang - Biomedicine & …, 2018 - Elsevier
MicroRNAs (miRNAs) have been widely studied in various human cancers, including
bladder cancer. Previous report revealed that miR-125a-5p is downregulated in urothelial …

Role of microRNAs in trophoblast invasion and spiral artery remodeling: implications for preeclampsia

H Hayder, Y Shan, Y Chen, JA O'Brien… - Frontiers in Cell and …, 2022 - frontiersin.org
It is now well-established that microRNAs (miRNAs) are important regulators of gene
expression. The role of miRNAs in placental development and trophoblast function is …

Post‐transcriptional regulation of polycistronic microRNAs

M Vilimova, S Pfeffer - Wiley Interdisciplinary Reviews: RNA, 2023 - Wiley Online Library
An important proportion of microRNA (miRNA) genes tend to lie close to each other within
animal genomes. Such genomic organization is generally referred to as miRNA clusters …

Regulation and tumor‐suppressive function of the miR‐379/miR‐656 (C14MC) cluster in cervical cancer

S Srinath, PV Jishnu, VK Varghese, V Shukla… - Molecular …, 2024 - Wiley Online Library
Cervical cancer (CC) is a key contributor to cancer‐related mortality in several countries.
The identification of molecular markers and the underlying mechanism may help improve …

Unravelling the mosaic: Epigenetic diversity in glioblastoma

S Lucchini, M Constantinou, S Marino - Molecular Oncology, 2024 - Wiley Online Library
Glioblastoma is the most common primary malignant brain tumour. Despite decades of
intensive research in the disease, its prognosis remains poor, with an average survival of …

Applications of CRISPR-Cas9 technology to genome editing in glioblastoma multiforme

N Al-Sammarraie, SK Ray - Cells, 2021 - mdpi.com
Glioblastoma multiforme (GBM) is an aggressive malignancy of the brain and spinal cord
with a poor life expectancy. The low survivability of GBM patients can be attributed, in part, to …

CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis

R Liu, W Dai, A Wu, Y Li - BMC cancer, 2021 - Springer
Background Glioblastoma (GBM) is characterized by progressive growth and metastasis.
Numerous studies claim that the deregulation of circular RNAs (circRNAs) is associated with …