Candida albicans is a diploid human fungal pathogen that displays significant genomic and
phenotypic heterogeneity over a range of virulence traits and in the context of a variety of …

Fungi were some of the earliest organismal systems used to explore mutational processes
and its phenotypic consequences on members of a species. Yeasts that cause significant …

Candida albicans is a ubiquitous fungus of humans. It is not only a component of the oral
and intestinal microbiota of most healthy adults but also a major cause of mucosal disorders …

Candida albicans is the most abundant fungal species in oral cavity. As a smart
opportunistic pathogen, it increases the virulence by switching its forms from yeasts to …

Major Candida albicans virulence traits include its ability to make hyphae, to produce a
biofilm, and to damage host cells. These traits depend upon expression of hypha-associated …

Iron acquisition is critical for pathogens to proliferate during invasive infection, and the
human fungal pathogen Candida albicans is no exception. The iron regulatory network …

RNA interference (RNAi) is a fundamental regulatory pathway with a wide range of
functions, including regulation of gene expression and maintenance of genome stability …

Formation of hyphae is a key virulence trait of the fungal pathogen Candida albicans. Hypha
morphogenesis depends upon the cyclin Hgc1, which acts together with cyclin-dependent …

Biofilm formation by the fungal pathogen Candida albicans is the basis for its ability to infect
medical devices. The metabolic gene ERG251 has been identified as a target of biofilm …

Candida albicans is a leading cause of intravascular catheter-related infections. The
capacity for biofilm formation has been proposed to contribute to the persistence of this …