Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China

L Yang, Z Wang - European journal of medicinal chemistry, 2023 - Elsevier
The ongoing COVID-19 pandemic has resulted in millions of deaths globally, highlighting
the need to develop potent prophylactic and therapeutic strategies against SARS-CoV-2 …

Chinese herbal medicine: Fighting SARS-CoV-2 infection on all fronts

Z Wang, L Yang - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection causes coronavirus disease 2019 (COVID-19), a highly pathogenic virus …

Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection

JT Jan, TJR Cheng, YP Juang, HH Ma… - Proceedings of the …, 2021 - National Acad Sciences
The outbreak of COVID-19 caused by SARS-CoV-2 has resulted in more than 50 million
confirmed cases and over 1 million deaths worldwide as of November 2020. Currently, there …

A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS …

KS Kim, K Ejima, S Iwanami, Y Fujita, H Ohashi… - PLoS …, 2021 - journals.plos.org
The scientific community is focused on developing antiviral therapies to mitigate the impacts
of the ongoing novel coronavirus disease 2019 (COVID-19) outbreak. This will be facilitated …

In Silico Exploration of the Molecular Mechanism of Clinically Oriented Drugs for Possibly Inhibiting SARS-CoV-2's Main Protease

T Huynh, H Wang, B Luan - The Journal of Physical Chemistry …, 2020 - ACS Publications
Currently, the new coronavirus disease 2019 (COVID-19) is a global pandemic without any
well-calibrated treatment. To inactivate the SARS-CoV-2 virus that causes COVID-19, the …

A review of therapeutic agents and Chinese herbal medicines against SARS-COV-2 (COVID-19)

F Huang, Y Li, ELH Leung, X Liu, K Liu, Q Wang… - Pharmacological …, 2020 - Elsevier
The epidemic of pneumonia (COVID-19) caused by novel coronavirus (SARS-CoV-2)
infection has been listed as a public health emergency of international concern by the World …

Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles

CZ Chen, M Xu, M Pradhan, K Gorshkov… - ACS Pharmacology & …, 2020 - ACS Publications
While vaccine development will hopefully quell the global pandemic of COVID-19 caused by
SARS-CoV-2, small molecule drugs that can effectively control SARS-CoV-2 infection are …

Targeting proteases for treating COVID-19

B Luan, T Huynh, X Cheng, G Lan… - Journal of proteome …, 2020 - ACS Publications
The unprecedented pandemic of coronavirus disease 2019 (COVID-19) demands effective
treatment for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The …

[HTML][HTML] A comprehensive review on the global efforts on vaccines and repurposed drugs for combating COVID-19

ND Kushwaha, J Mohan, B Kushwaha, T Ghazi… - European Journal of …, 2023 - Elsevier
The recently discovered coronavirus, known as SARS-CoV-2, is a highly contagious and
potentially lethal viral infection that was declared a pandemic by the World Health …

The potential of antiviral peptides as COVID-19 therapeutics

ASK Mahendran, YS Lim, CM Fang, HS Loh… - Frontiers in …, 2020 - frontiersin.org
To date, more than 17 million cases of coronavirus disease 2019 (COVID-19) and 900,000
deaths have been reported globally (World Health Organization, 2020). Major collaborative …