[HTML][HTML] Parkinson's disease: animal models and dopaminergic cell vulnerability
J Blesa, S Przedborski - Frontiers in neuroanatomy, 2014 - frontiersin.org
Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the
global population over 65 years of age. A hallmark feature of PD is the degeneration of the …
global population over 65 years of age. A hallmark feature of PD is the degeneration of the …
Evaluation of models of Parkinson's disease
Parkinson's disease is one of the most common neurodegenerative diseases. Animal
models have contributed a large part to our understanding and therapeutics developed for …
models have contributed a large part to our understanding and therapeutics developed for …
Increased risk of Parkinson's disease in individuals hospitalized with conditions related to the use of methamphetamine or other amphetamine-type drugs
RC Callaghan, JK Cunningham, J Sykes… - Drug and alcohol …, 2012 - Elsevier
BACKGROUND: Since methamphetamine and other amphetamine-type stimulants
(meth/amphetamine) can damage dopaminergic neurons, researchers have long …
(meth/amphetamine) can damage dopaminergic neurons, researchers have long …
[HTML][HTML] Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies
Methamphetamine (MA) is a extremely addictive psychostimulant drug with a significant
abuse potential. Long-term MA exposure can induce neurotoxic effects through oxidative …
abuse potential. Long-term MA exposure can induce neurotoxic effects through oxidative …
Protective role of metformin against methamphetamine induced anxiety, depression, cognition impairment and neurodegeneration in rat: the role of CREB/BDNF and …
S Keshavarzi, S Kermanshahi, L Karami… - Neurotoxicology, 2019 - Elsevier
Background Methamphetamine is a neuro-stimulant with neurodegenerative effects, and
ambiguous mechanism of action. Metformin is an antidiabetic agent with neuroprotective …
ambiguous mechanism of action. Metformin is an antidiabetic agent with neuroprotective …
The neuropathology of drug abuse
A Büttner - Neuropathology and applied neurobiology, 2011 - Wiley Online Library
A. Büttner (2011) Neuropathology and Applied Neurobiology37, 118–134 The
neuropathology of drug abuse Drug abuse represents a significant health issue. The major …
neuropathology of drug abuse Drug abuse represents a significant health issue. The major …
Molecular mechanisms and treatment strategies for methamphetamine‑induced neurodegeneration, inflammation and neurotoxicity
Methamphetamine (METH) is a highly addictive psychostimulant known for its profound
impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by …
impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by …
Methamphetamine and its immune-modulating effects
The recreational use of methamphetamine (METH, or ice) is a global burden. It pervades
and plagues contemporary society; it has been estimated that there are up to 35 million …
and plagues contemporary society; it has been estimated that there are up to 35 million …
Chronic methamphetamine effects on brain structure and function in rats
Methamphetamine (MA) addiction is a growing epidemic worldwide. Chronic MA use has
been shown to lead to neurotoxicity in rodents and humans. Magnetic resonance imaging …
been shown to lead to neurotoxicity in rodents and humans. Magnetic resonance imaging …
Rethinking dual disorders/pathology
N Szerman, J Martinez-Raga, L Peris… - Addictive Disorders & …, 2013 - journals.lww.com
Objective: Comorbidity of addictive disorders and other psychiatric disorders is very
common. The optimal treatment of patients with addiction disorders requires awareness of …
common. The optimal treatment of patients with addiction disorders requires awareness of …