Role of traditional Chinese medicine in bone regeneration and osteoporosis

Z Peng, R Xu, Q You - Frontiers in Bioengineering and Biotechnology, 2022 - frontiersin.org
According to World Health Organization (WHO), osteoporosis is a systematic bone disability
marked by reduced bone mass and microarchitectural degeneration of osseous cells, which …

Towards reproducible computational drug discovery

N Schaduangrat, S Lampa, S Simeon… - Journal of …, 2020 - Springer
The reproducibility of experiments has been a long standing impediment for further scientific
progress. Computational methods have been instrumental in drug discovery efforts owing to …

Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Huashi Baidu formula in the treatment of COVID-19

Q Tao, J Du, X Li, J Zeng, B Tan, J Xu… - Drug development and …, 2020 - Taylor & Francis
Abstract Purpose Huashi Baidu formula (HSBDF) was developed to treat the patients with
severe COVID-19 in China. The purpose of this study was to explore its active compounds …

In silico polypharmacology of natural products

J Fang, C Liu, Q Wang, P Lin… - Briefings in bioinformatics, 2018 - academic.oup.com
Natural products with polypharmacological profiles have demonstrated promise as novel
therapeutics for various complex diseases, including cancer. Currently, many gaps exist in …

Is acupuncture effective in the treatment of COVID-19 related symptoms? Based on bioinformatics/network topology strategy

Z Han, Y Zhang, P Wang, Q Tang… - Briefings in …, 2021 - academic.oup.com
Acupuncture is an important part of Chinese medicine that has been widely used in the
treatment of inflammatory diseases. During the coronavirus disease 2019 (COVID-19) …

[HTML][HTML] The discovery and characterization of a potent DPP-IV inhibitory peptide from oysters for the treatment of type 2 diabetes based on computational and …

Z Chen, X Su, W Cao, M Tan, G Zhu, J Gao, L Zhou - Marine Drugs, 2024 - mdpi.com
The inhibition of dipeptidyl peptidase-IV (DPP-IV) is a promising approach for regulating the
blood glucose levels in patients with type 2 diabetes (T2D). Oysters, rich in functional …

Machine learning and deep learning for brain tumor MRI image segmentation

MKH Khan, W Guo, J Liu, F Dong, Z Li… - Experimental …, 2023 - journals.sagepub.com
Brain tumors are often fatal. Therefore, accurate brain tumor image segmentation is critical
for the diagnosis, treatment, and monitoring of patients with these tumors. Magnetic …

Identifying molecular targets of Aspiletrein-derived steroidal saponins in lung cancer using network pharmacology and molecular docking-based assessments

I Iksen, W Witayateeraporn, T Wirojwongchai… - Scientific Reports, 2023 - nature.com
Lung cancer is one of the leading cancers and causes of cancer-related deaths worldwide.
Due to its high prevalence and mortality rate, its clinical management remains a significant …

Dual-channel hypergraph convolutional network for predicting herb–disease associations

L Hu, M Zhang, P Hu, J Zhang, C Niu… - Briefings in …, 2024 - academic.oup.com
Herbs applicability in disease treatment has been verified through experiences over
thousands of years. The understanding of herb–disease associations (HDAs) is yet far from …

Results of the Seventh Scientific Workshop of ECCO: precision medicine in IBD—what, why, and how

C Fiocchi, G Dragoni, D Iliopoulos… - Journal of Crohn's …, 2021 - academic.oup.com
Many diseases that affect modern humans fall in the category of complex diseases, thus
called because they result from a combination of multiple aetiological and pathogenic …