Lactate dehydrogenase (LDH) is one of the crucial enzymes in aerobic glycolysis, catalyzing
the last step of glycolysis, ie. the conversion of pyruvate to lactate. Most cancer cells are …

Tumor cells must generate sufficient ATP and biosynthetic precursors in order to maintain
cell proliferation requirements. Otto Warburg showed that tumor cells uptake high amounts …

Breast cancer (BC) is the most prevalent cancer in women. BC is heterogeneous, with
distinct phenotypical and morphological characteristics. These are based on their gene …

The definition for autophagy holds a 'single'meaning as a conserved cellular process that
constitutes a recycling pathway for damaged organelles and long-lived proteins to maintain …

Tamoxifen is a drug commonly used in the treatment of breast cancer, especially for
postmenopausal patients. However, its efficacy is limited by the development of drug …

Simple Summary The metabolism of carbohydrates and lipids is essential to meet the
diverse needs of cells. The autophagy cellular pathway is crucial for normal cellular function …

Background Lysine succinylation is an emerging posttranslational modification that has
garnered increased attention recently, but its role in gastric cancer (GC) remains …

Tumor cells often switch from mitochondrial oxidative metabolism to glycolytic metabolism
even under aerobic conditions. Tumor cell glycolysis is accompanied by several …

Papillary thyroid carcinoma (PTC) is one of the most common kinds of endocrine-related
cancer and has a heterogeneous prognosis. Metabolic reprogramming is one of the …

Simple Summary Glucose metabolic reprogramming is a process in which cells alter the way
that glucose is utilized. In breast cancer, cells can undergo this process to fuel their growth …