Several advances in fluid and tissue-based biomarkers for use in Parkinson's disease (PD)
and other synucleinopathies have been made in the last several years. While work …

The possible usefulness of alpha-synuclein (aSyn) determinations in peripheral tissues
(blood cells, salivary gland biopsies, olfactory mucosa, digestive tract, skin) and in biological …

The diagnosis and follow-up of peripheral neuropathies involving small-diameter nerve
fibers require specific examinations beyond conventional nerve conduction studies which …

Parkinson disease (PD) is the second most common neurodegenerative disorder in elderly
people. It is characterized by the aggregation of misfolded alpha-synuclein throughout the …

Alpha-synuclein deposits are detectable in skin biopsies of patients with Parkinson's
disease and other synucleinopathies like multiple system atrophy by immunohistochemical …

Background Cytoplasmic inclusions of α‐synuclein (α‐syn) in brainstem neurons are
characteristic of idiopathic Parkinson's disease (PD). PD also entails α‐syn buildup in …

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
presence of α-synuclein (α-Syn)-rich Lewy bodies (LBs) and the preferential loss of …

Objective This study aimed to analyze the association of autonomic dysfunction with
cognition, depression, apathy, and fatigue in Lewy body disease (LBD). Methods We …

Parkinson's disease (PD) is the second most common neurodegenerative disease in the
elder population, pathologically characterized by the progressive loss of dopaminergic …

Objective Recent studies demonstrated cutaneous phosphorylated α synuclein (p‐syn)
deposition in idiopathic and some monogenetic Parkinson disease (PD) patients …