[HTML][HTML] Downstream processing technologies in the biocatalytic production of oligosaccharides

A Kruschitz, B Nidetzky - Biotechnology Advances, 2020 - Elsevier
Oligosaccharides are important ingredients for food and feed products. There has therefore
been much interest in the development of biocatalytic processes for their production …

Continuous downstream bioprocessing for intensified manufacture of biopharmaceuticals and antibodies

L Gerstweiler, J Bi, APJ Middelberg - Chemical Engineering Science, 2021 - Elsevier
Continuous production delivers higher productivity and better quality than traditional batch-
wise approaches. It intensifies production lowering capital cost and enables better control …

Enzyme membrane reactors for production of oligosaccharides: A review on the interdependence between enzyme reaction and membrane separation

Z Su, J Luo, X Li, M Pinelo - Separation and Purification Technology, 2020 - Elsevier
Certain types of oligosaccharides are especially interesting due to their high commercial
value, however, the traditional oligosaccharide fabrication process is neither sustainable nor …

Review of membrane separation models and technologies: Processing complex food-based biomolecular fractions

SRCK Rajendran, B Mason, AA Doucette - Food and Bioprocess …, 2021 - Springer
There is growing interest in the food industry to develop approaches for large-scale
production of bioactive molecules through continuous downstream processing, especially …

[HTML][HTML] Model-based optimization approaches for pressure-driven membrane systems

Z Rizki, M Ottens - Separation and Purification Technology, 2023 - Elsevier
Membrane technology is commonly used within food, bio-and pharmaceutical processes.
Beside single-stage membranes, multi-stage membrane systems are become more popular …

[HTML][HTML] Multi-criteria design of membrane cascades: Selection of configurations and process parameters

Z Rizki, AEM Janssen, GDH Claassen… - Separation and …, 2020 - Elsevier
Membrane cascades can fractionate fructooligosaccharides into 3 different fractions with
varying degrees of polymerization (DP). In contrast to the traditional membrane system …

[HTML][HTML] Modelling temperature effects in a membrane cascade system for oligosaccharides

Z Rizki, E Suryawirawan, AEM Janssen… - Journal of Membrane …, 2020 - Elsevier
Open nanofiltration of mixtures of fructo-oligosaccharides was assessed by experiment and
by modelling the overall permeation behaviour of 3 different membranes. The temperature …

[HTML][HTML] Design optimization of a 3-stage membrane cascade for oligosaccharides purification using mixed integer non-linear programming

Z Rizki, AEM Janssen, EMT Hendrix… - Chemical Engineering …, 2021 - Elsevier
Inhomogeneous membrane cascade systems have been utilized to purify
fructooligosaccharides (FOS). Such a process allows a different setup at every stage of the …

[HTML][HTML] Design of nanofiltration cascades for fructooligosaccharides using the McCabe-Thiele approach

Z Rizki, AEM Janssen, A van der Padt… - Separation and …, 2021 - Elsevier
We developed a design method for an inhomogeneous membrane cascade by adopting the
McCabe-Thiele method, which is long established for designing distillation columns. The …

Separation of fructose and glucose via nanofiltration in presence of fructooligosaccharides

Z Rizki, AEM Janssen, A van der Padt, RM Boom - Membranes, 2020 - mdpi.com
Fructose and glucose are commonly present together in mixtures and may need to be
separated. Current separation methods for these isomers are complex and costly …