Nanoparticles engineering by pulsed laser ablation in liquids: Concepts and applications

E Fazio, B Gökce, A De Giacomo, M Meneghetti… - Nanomaterials, 2020 - mdpi.com
Laser synthesis emerges as a suitable technique to produce ligand-free nanoparticles,
alloys and functionalized nanomaterials for catalysis, imaging, biomedicine, energy and …

[HTML][HTML] Not only in silico drug discovery: Molecular modeling towards in silico drug delivery formulations

T Casalini - Journal of Controlled Release, 2021 - Elsevier
The use of methods at molecular scale for the discovery of new potential active ligands, as
well as previously unknown binding sites for target proteins, is now an established reality …

Biohybrid nanocellulose–lysozyme amyloid aerogels via electrostatic complexation

L Severini, KJ De France, D Sivaraman, N Kummer… - ACS …, 2021 - ACS Publications
Modern science is increasingly turning to nature for inspiration to design sustainable
biomaterials in a smart and effective way. Herein, we describe biohybrid aerogels based on …

SERS nanostructures with engineered active peptides against an immune checkpoint protein

M Gobbo, I Caligiuri, M Giannetti, L Litti, C Mazzuca… - Nanoscale, 2024 - pubs.rsc.org
The immune checkpoint programmed death ligand 1 (PD-L1) protein is expressed by tumor
cells and it suppresses the killer activity of CD8+ T-lymphocyte cells binding to the …

Urokinase plasminogen activator receptor-mediated targeting of a stable nanocomplex coupled with specific peptides for imaging of cancer

D Shahdeo, AB Chandra, S Gandhi - Analytical Chemistry, 2021 - ACS Publications
Targeting peptides are a promising tool for early diagnosis and therapy of cancer.
Overexpression of urokinase plasminogen activator receptor (uPAR) leads to the …

PreS1 peptide-functionalized gold nanostructures with SERRS tags for efficient liver cancer cell targeting

F Biscaglia, S Quarta, G Villano, C Turato… - Materials Science and …, 2019 - Elsevier
Early detection is the most effective mean of improving prognosis for many fatal diseases
such as cancer. In this context, the Surface Enhanced Resonance Raman Scattering …

Targeted polymer-based probes for fluorescence guided visualization and potential surgery of EGFR-positive head-and-neck tumors

R Pola, E Böhmová, M Filipová, M Pechar, J Pankrác… - Pharmaceutics, 2020 - mdpi.com
This report describes the design, synthesis and evaluation of tumor-targeted polymer probes
to visualize epidermal growth factor receptor (EGFR)-positive malignant tumors for …

A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles

M Kanada, L Linenfelser, E Cox, AA Gilad - Pharmaceutics, 2022 - mdpi.com
Extracellular vesicle (EV)-mediated transfer of biomolecules plays an essential role in
intercellular communication and may improve targeted drug delivery. In the past decade …

Protection against proteolysis of a targeting peptide on gold nanostructures

F Biscaglia, I Caligiuri, F Rizzolio, G Ripani, A Palleschi… - Nanoscale, 2021 - pubs.rsc.org
Cell targeting has been considered an important strategy in diagnostic and therapeutic
applications. Among different targeting units, peptides have emerged for their ability to bind …

From nanoaggregates to mesoscale ribbons: the multistep self-organization of amphiphilic peptides

GML Messina, C Mazzuca, M Dettin, A Zamuner… - Nanoscale …, 2021 - pubs.rsc.org
This paper reports atomic force microscopy results and molecular dynamics simulations of
the striking differences of long-term self-organization structures of negatively charged (AcA4) …